{"id":"W2981183570","doi":"10.3389/fimmu.2019.02486","title":"Foxp3 Post-translational Modifications and Treg Suppressive Activity","year":2019,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":157,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Peking University Health Science Center; Peking University","keywords":"FOXP3; Immune system; Autoimmunity; Regulator; Biology; Transcription factor; Cell biology; Regulatory T cell; Immunology; Immune tolerance; Cancer research; T cell; IL-2 receptor; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002368797,0.0004882335,0.0005547588,0.001004572,0.0001725563,0.0004791912,0.0004095315,0.000536348,0.002510589],"category_scores_gemma":[0.0002731101,0.0001306627,0.0002184238,0.0008952334,0.0003040626,0.0005760339,0.0003878978,0.0009812252,0.001362082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004329104,"about_ca_system_score_gemma":0.0006971217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005721609,"about_ca_topic_score_gemma":0.0007559782,"domain_scores_codex":[0.999925,0.00001015698,0.000008429205,0.00001544094,0.00002880987,0.00001206068],"domain_scores_gemma":[0.9999214,0.00002801725,0.00001325185,0.000002667125,0.00002066319,0.00001398711],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009410236,0.00004221542,0.0002438443,0.008012519,0.00003370069,0.0002516173,0.0000413368,0.0002503344,0.007006536,0.003650703,0.01828208,0.962091],"study_design_scores_gemma":[0.00001423917,0.00008634885,0.00146738,0.001237586,0.00004801997,0.001850593,0.00003963781,0.00009582991,0.001858396,0.002488444,0.9908013,0.0000121809],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003812691,0.9971101,0.000232083,0.0002918302,0.0003047855,0.000003757792,0.00002368795,0.00001281897,0.001639685],"genre_scores_gemma":[0.002668862,0.9951473,0.0002529639,0.0002283125,0.0002839326,0.00000692976,0.00006331906,0.000002295907,0.001346104],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002510589,"threshold_uncertainty_score":0.008398712,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02442364524093498,"score_gpt":0.2690612638526582,"score_spread":0.2446376186117232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}