{"id":"W2981207334","doi":"10.1111/bph.14888","title":"Dietary antioxidants remodel DNA methylation patterns in chronic disease","year":2019,"lang":"en","type":"review","venue":"British Journal of Pharmacology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Center for Advancing Translational Sciences","keywords":"Epigenetics; DNA methylation; Epigenome; Biology; Methylation; Oxidative stress; Epigenomics; Antioxidant; Chromatin; Bioinformatics; Genetics; DNA; Gene expression; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006171118,0.0002640126,0.0009409826,0.0002207013,0.0000374356,0.000030946,0.0003435281,0.0003456542,0.00007133602],"category_scores_gemma":[0.0000657935,0.0002961696,0.0004979872,0.0001279924,0.00004115659,0.00001197691,0.0001135415,0.0004865115,0.00001005662],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001547965,"about_ca_system_score_gemma":0.0008856123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001525994,"about_ca_topic_score_gemma":0.00003642062,"domain_scores_codex":[0.9975994,0.0005641013,0.0009907625,0.0003505715,0.0001912889,0.0003039207],"domain_scores_gemma":[0.9986527,0.00004808014,0.0008813069,0.0001306655,0.0001480122,0.0001392484],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004254966,0.0001032722,0.00005605602,0.003104426,0.0002149601,0.0003300194,0.000004234519,0.0003314257,0.02317123,5.711283e-7,0.0005321801,0.9721091],"study_design_scores_gemma":[0.001950891,0.0005356062,0.001288824,0.006344708,0.001548291,0.0004403297,0.000003735381,0.0001547429,0.00373235,0.00006741579,0.9832676,0.0006654804],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02351002,0.9745022,0.0003366287,0.00001853472,0.001074458,0.000400913,0.0001139437,0.000002760017,0.00004050635],"genre_scores_gemma":[0.01855021,0.9795938,0.00008091053,0.00004603125,0.001263399,0.00001268762,0.0002585379,0.00005462396,0.0001398166],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9827355,"threshold_uncertainty_score":0.999949,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05087909192379914,"score_gpt":0.3747493499809003,"score_spread":0.3238702580571011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}