{"id":"W2981424470","doi":"10.1128/mbio.02059-19","title":"Oseltamivir Is Effective against 1918 Influenza Virus Infection of Macaques but Vulnerable to Escape","year":2019,"lang":"en","type":"article","venue":"mBio","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Canadian Food Inspection Agency; University of Manitoba; Public Health Agency of Canada","funders":"","keywords":"Oseltamivir; Pandemic; Virology; Virus; Vaccination; Medicine; Influenza A virus subtype H5N1; Immunology; Intensive care medicine; Coronavirus disease 2019 (COVID-19); Disease; Infectious disease (medical specialty); Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000494332,0.0002296533,0.0005176269,0.0003273368,0.0001229112,0.00002317229,0.0001054071,0.0001367491,0.0003346425],"category_scores_gemma":[0.0005940542,0.0001966551,0.0001411882,0.0004752458,0.00009384166,0.000157247,0.0001821083,0.0004234877,0.001866667],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000224268,"about_ca_system_score_gemma":0.00008284656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002953914,"about_ca_topic_score_gemma":0.0001201629,"domain_scores_codex":[0.9981876,0.0001394783,0.0003299008,0.0003796933,0.0005099167,0.0004533863],"domain_scores_gemma":[0.9986687,0.0002165146,0.00009377548,0.0004686396,0.0003889448,0.000163386],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00107137,0.0003039227,0.3227109,0.0006725484,0.0004741381,0.0000174441,0.002423293,0.0001209946,0.6328994,0.00008253536,0.009647965,0.02957548],"study_design_scores_gemma":[0.002379638,0.001478705,0.192507,0.0003348199,0.00006200704,0.000004623215,0.0001169262,0.0001417463,0.7085312,0.00005874182,0.09410886,0.0002758003],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9711372,0.0004124172,0.00003519322,0.0001502897,0.0001950283,0.001564922,0.00004726624,0.0001009362,0.02635672],"genre_scores_gemma":[0.9920292,0.0002309783,0.0002080251,0.00467416,0.0001505203,0.0001482069,0.000007935673,0.00003948809,0.002511433],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1302039,"threshold_uncertainty_score":0.9989105,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03287232543286994,"score_gpt":0.3582553457879065,"score_spread":0.3253830203550366,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}