{"id":"W2981524970","doi":"10.1534/g3.119.400635","title":"Identification of Genes Required for Apical Protein Trafficking in <i>Drosophila</i> Photoreceptor Cells","year":2019,"lang":"en","type":"article","venue":"G3 Genes Genomes Genetics","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Cell biology; Exocyst; Apical membrane; Biology; Schneider 2 cells; Secretion; Rab; Endosome; Endocytosis; RNA interference; Vacuole; Cilium; Epithelial polarity; Drosophila melanogaster; Photoreceptor cell; Transport protein; Apical constriction; Membrane protein; Retina; Gene; Cytoplasm; Cell; Exocytosis; Genetics; Epithelium; Morphogenesis; Biochemistry; GTPase; Membrane; Intracellular","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000776622,0.0005463777,0.000282615,0.000501443,0.0002039718,0.0002741333,0.0002883141,0.0003259071,0.001589724],"category_scores_gemma":[0.0001369689,0.0002807206,0.0003243378,0.0001899102,0.0003073631,0.000109892,0.0002322732,0.000462401,0.0007591032],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000509349,"about_ca_system_score_gemma":0.0003270479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002012225,"about_ca_topic_score_gemma":0.003240503,"domain_scores_codex":[0.9998424,0.00001290598,0.00001918227,0.00004317337,0.00005088575,0.00003139986],"domain_scores_gemma":[0.999764,0.00006395999,0.00007762443,0.00002014399,0.00001694582,0.00005738889],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002918721,0.000009552725,0.000283072,0.00001661111,0.000003150761,0.0001278289,0.000006685139,0.0000438598,0.9987679,0.00005023739,0.00003001814,0.0006318986],"study_design_scores_gemma":[0.00003032051,0.0001178336,0.04334688,0.00001615207,0.00005629021,0.001083133,0.00005622035,0.0009207993,0.9486957,0.00007377267,0.005584814,0.00001805451],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877841,0.001225619,0.00422297,0.0001254383,0.00002898487,0.00007407578,0.003959517,0.0002693955,0.002309788],"genre_scores_gemma":[0.9815814,0.0008710144,0.006174971,0.0001876686,0.00001265312,0.00007573203,0.006478922,0.0002171497,0.004400544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002012225,"threshold_uncertainty_score":0.005318105,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009974859843518969,"score_gpt":0.2356670111738391,"score_spread":0.2256921513303201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}