{"id":"W2981569509","doi":"10.1055/a-1025-0119","title":"A Pharmacokinetic Evaluation of Dabigatran Etexilate, Total Dabigatran, and Unconjugated Dabigatran Following the Administration of Dabigatran Etexilate Mesylate Capsules in Healthy Male and Female Subjects","year":2019,"lang":"en","type":"article","venue":"Drug Research","topic":"Atrial Fibrillation Management and Outcomes","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Pharma Medica Research (Canada)","funders":"","keywords":"Dabigatran; Pharmacokinetics; Medicine; Cmax; Pharmacology; Mesylate; Bioequivalence; Dosing; Tolerability; Anesthesia; Adverse effect; Internal medicine; Warfarin; Chemistry; Atrial fibrillation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003670361,0.0004010971,0.0004393548,0.0001475956,0.0002374837,0.0003145432,0.0001055076,0.000308576,0.0009079752],"category_scores_gemma":[0.0006618971,0.0002253914,0.0002021828,0.0001494202,0.0002691074,0.0002005619,0.0001033465,0.0002880841,0.0002757659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001577084,"about_ca_system_score_gemma":0.0003279977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007559111,"about_ca_topic_score_gemma":0.0008151702,"domain_scores_codex":[0.9997028,0.00008877372,0.00001533298,0.00007868051,0.0000917488,0.0000225801],"domain_scores_gemma":[0.9997855,0.0000415318,0.00005688109,0.00002439024,0.00003703848,0.0000547271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0402866,0.004721092,0.1005791,0.0004180124,0.0005401936,0.001299931,0.001118938,0.0009325821,0.7569894,0.0001698588,0.0005437878,0.09240041],"study_design_scores_gemma":[0.002163661,0.1097922,0.758524,0.00002831635,0.0005396682,0.005620783,0.0004349143,0.004535768,0.1138299,0.0001190788,0.004332774,0.00007886512],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983742,0.0005546991,0.000616823,0.00001615075,0.000008975363,0.00007129446,0.00008472637,0.00001411449,0.0002589227],"genre_scores_gemma":[0.9980745,0.000309607,0.0007048023,0.00004218076,0.0000133501,0.00004770316,0.000140615,0.000005401588,0.000661723],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009079752,"threshold_uncertainty_score":0.003037512,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1349473098415331,"score_gpt":0.4471364936537274,"score_spread":0.3121891838121943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}