{"id":"W2981583476","doi":"10.1007/s10549-019-05472-w","title":"Untapped “-omics”: the microbial metagenome, estrobolome, and their influence on the development of breast cancer and response to treatment","year":2019,"lang":"en","type":"review","venue":"Breast Cancer Research and Treatment","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; Sunnybrook Hospital; McMaster University","funders":"","keywords":"Breast cancer; Dysbiosis; Microbiome; Metagenomics; Cancer; Estrogen receptor; Bioinformatics; Biology; Carcinogenesis; Medicine; Computational biology; Internal medicine; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001044299,0.0009626109,0.001991057,0.001541845,0.0001782179,0.001645945,0.0008325719,0.001490694,0.002942628],"category_scores_gemma":[0.001412245,0.0002674515,0.0006536552,0.00198964,0.0005720778,0.00145123,0.0009352847,0.002252948,0.001333419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008201001,"about_ca_system_score_gemma":0.001523202,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001609999,"about_ca_topic_score_gemma":0.003246283,"domain_scores_codex":[0.9997289,0.00006787132,0.00003073066,0.00005110313,0.00009086579,0.00003055346],"domain_scores_gemma":[0.9991193,0.0004999333,0.00009893737,0.00002636143,0.0001880422,0.00006737813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001673008,0.00004644273,0.0003163046,0.01411137,0.0002593009,0.00009944624,0.0000409561,0.0002941329,0.002006263,0.005535311,0.03313847,0.9439847],"study_design_scores_gemma":[0.00002987962,0.0001035728,0.001687468,0.005994547,0.0002806252,0.0005028112,0.00008137769,0.0001816029,0.0006573618,0.004912625,0.9855347,0.00003347061],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006698737,0.9987546,0.00011038,0.0004910951,0.0002723968,0.00000163137,0.0000288097,0.000005224452,0.0002687561],"genre_scores_gemma":[0.0005097523,0.9982169,0.0001602654,0.000418572,0.0003569662,0.000003099111,0.00004220187,0.000001589303,0.0002905601],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002942628,"threshold_uncertainty_score":0.009844065,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0811881164033844,"score_gpt":0.3941267669548926,"score_spread":0.3129386505515082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}