{"id":"W2981626013","doi":"10.1182/bloodadvances.2019000593","title":"Safety of allogeneic hematopoietic cell transplant in adults after CD19-targeted CAR T-cell therapy","year":2019,"lang":"en","type":"article","venue":"Blood Advances","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":100,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute","keywords":"Hematopoietic cell; CAR T-cell therapy; CD19; Medicine; Cell therapy; Hematopoietic stem cell transplantation; Genetic enhancement; Haematopoiesis; Oncology; Toxicity; Chimeric antigen receptor; Internal medicine; Immunology; Transplantation; Stem cell; T cell; Peripheral blood; Biology; Gene; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001206051,0.0001277458,0.0003405912,0.0001531842,0.0001759106,0.0004521671,0.0001324081,0.0002653881,0.0005627533],"category_scores_gemma":[0.002957657,0.00004678174,0.0002341389,0.0002244947,0.0001810523,0.0002169501,0.0001878465,0.0003176472,0.0002035901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002743759,"about_ca_system_score_gemma":0.0002646115,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002245778,"about_ca_topic_score_gemma":0.0002666186,"domain_scores_codex":[0.9994429,0.0002478209,0.00008638178,0.00004960768,0.0001192245,0.0000540179],"domain_scores_gemma":[0.9979107,0.0007567321,0.0007959417,0.00009453434,0.0001991838,0.0002429607],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.006141093,0.0002345361,0.7048656,0.0003898328,0.0001833352,0.005097098,0.0005875013,0.001374898,0.01372081,0.0006198165,0.001491253,0.2652943],"study_design_scores_gemma":[0.0004821836,0.04208995,0.8468137,0.00043613,0.0006413361,0.04831869,0.0007932982,0.004318224,0.026521,0.0009941567,0.02855823,0.00003308175],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876339,0.00865138,0.001337386,0.0002329198,0.00003474355,0.00001954841,0.0001460362,0.00002862765,0.001915459],"genre_scores_gemma":[0.9982962,0.0009837946,0.0002340374,0.0001397483,0.00004768869,0.000008118174,0.0001645827,0.00000473809,0.0001210856],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001206051,"threshold_uncertainty_score":0.006378293,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006991509777375879,"score_gpt":0.2490289107636882,"score_spread":0.2420374009863124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}