{"id":"W2981644785","doi":"10.1016/j.conctc.2019.100478","title":"Rationale and design of an international randomized placebo-controlled trial of a 36-ingredient micronutrient supplement for children with ADHD and irritable mood: The Micronutrients for ADHD in Youth (MADDY) study","year":2019,"lang":"en","type":"article","venue":"Contemporary Clinical Trials Communications","topic":"Attention Deficit Hyperactivity Disorder","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge","funders":"National Center for Complementary and Integrative Health; National Institutes of Health; Calgary Foundation; Foundation for Excellence in Mental Health Care; Nationwide Children's Hospital; Ohio State University; National Center for Advancing Translational Sciences; Center for Clinical and Translational Science, Ohio State University; Oregon Health and Science University; Wells Fargo; Nationwide","keywords":"Irritability; Randomized controlled trial; Micronutrient; Mood; Psychiatry; Clinical psychology; Medicine; Attention deficit hyperactivity disorder; Placebo; Psychology; Aggression; Anxiety; Internal medicine; Alternative medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01729221,0.000204182,0.002066231,0.0001807121,0.0001071353,0.00003455028,0.0004009728,0.0001066646,0.00001713194],"category_scores_gemma":[0.006727676,0.0001340832,0.0003352574,0.0001279032,0.000344303,0.0002141255,0.000176998,0.0002162596,4.257955e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002856273,"about_ca_system_score_gemma":0.0003417753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001091925,"about_ca_topic_score_gemma":0.0000360416,"domain_scores_codex":[0.9929296,0.00351272,0.002718943,0.0003960666,0.0002888668,0.0001538383],"domain_scores_gemma":[0.979022,0.01798761,0.001446652,0.001017169,0.0004400841,0.00008644934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9735064,0.007392822,0.01400759,0.0000292156,0.00144199,1.060999e-7,0.002762686,0.00003444501,0.0001404771,0.000244886,0.0001156734,0.0003236925],"study_design_scores_gemma":[0.9792562,0.004289138,0.001844527,0.0001336585,0.0008318248,0.000001981527,0.009864029,0.003193328,0.00003930859,0.0002131272,0.0002003235,0.000132527],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9287735,0.0006227881,0.003234789,0.002790265,0.0001894318,0.06374785,0.0005839776,0.00001239309,0.00004496728],"genre_scores_gemma":[0.9883137,0.0002417983,0.006603541,0.0000661357,0.00009335781,0.003794132,0.0007461052,0.000024499,0.0001167572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05995372,"threshold_uncertainty_score":0.8054143,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2868979000028196,"score_gpt":0.456926366397084,"score_spread":0.1700284663942644,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}