{"id":"W2981644785","doi":"10.1016/j.conctc.2019.100478","title":"Rationale and design of an international randomized placebo-controlled trial of a 36-ingredient micronutrient supplement for children with ADHD and irritable mood: The Micronutrients for ADHD in Youth (MADDY) study","year":2019,"lang":"en","type":"article","venue":"Contemporary Clinical Trials Communications","topic":"Attention Deficit Hyperactivity Disorder","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Lethbridge","funders":"National Center for Complementary and Integrative Health; National Institutes of Health; Calgary Foundation; Foundation for Excellence in Mental Health Care; Nationwide Children's Hospital; Ohio State University; National Center for Advancing Translational Sciences; Center for Clinical and Translational Science, Ohio State University; Oregon Health and Science University; Wells Fargo; Nationwide","keywords":"Irritability; Randomized controlled trial; Micronutrient; Mood; Psychiatry; Clinical psychology; Medicine; Attention deficit hyperactivity disorder; Placebo; Psychology; Aggression; Anxiety; Internal medicine; Alternative medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.081599,0.007673626,0.008791122,0.002640645,0.003886062,0.004031063,0.004400361,0.00867528,0.02475834],"category_scores_gemma":[0.05538961,0.004163141,0.00564577,0.001984398,0.00662102,0.003841233,0.00235301,0.008539844,0.005689113],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003256674,"about_ca_system_score_gemma":0.0152717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00146777,"about_ca_topic_score_gemma":0.002594409,"domain_scores_codex":[0.9410397,0.04171958,0.004294921,0.005036162,0.005171679,0.002737921],"domain_scores_gemma":[0.9783211,0.00799094,0.003705263,0.002850021,0.004039833,0.003092801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"not_applicable","study_design_scores_codex":[0.8535329,0.02239546,0.004029166,0.02358225,0.004681045,0.0004832107,0.0009229738,0.002899599,0.004272112,0.01760141,0.01123769,0.05436228],"study_design_scores_gemma":[0.8837243,0.06124815,0.002787402,0.002841321,0.003800241,0.0001054235,0.0001790054,0.002715941,0.001509312,0.007547303,0.03337975,0.0001618781],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.003604367,0.0008657501,0.003369126,0.0006952269,0.001028647,0.9882714,0.0006208359,0.00007944611,0.001465061],"genre_scores_gemma":[0.006669116,0.0002773246,0.007019379,0.0007350541,0.0001546242,0.9846028,0.0001178699,0.000005183661,0.0004186487],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.081599,"threshold_uncertainty_score":0.4315419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2868979000028196,"score_gpt":0.456926366397084,"score_spread":0.1700284663942644,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}