{"id":"W2981646850","doi":"10.1261/rna.072199.119","title":"An RNA guanine quadruplex regulated pathway to TRAIL-sensitization by DDX21","year":2019,"lang":"en","type":"article","venue":"RNA","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Biology; Cell biology; RNA; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007255769,0.0001443003,0.0001249542,0.00001745774,0.00003766755,0.00002437288,0.0001647722,0.0001771908,0.0002405438],"category_scores_gemma":[0.00002251234,0.0001450553,0.00004985436,0.00008626567,0.00002030805,0.000005012719,0.00004165023,0.00005848952,0.0001211362],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001368128,"about_ca_system_score_gemma":0.00002943507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001541115,"about_ca_topic_score_gemma":0.000005698821,"domain_scores_codex":[0.9991289,0.00002261875,0.0001553621,0.0003594962,0.0001156805,0.0002179722],"domain_scores_gemma":[0.9992915,0.000003728483,0.00005148514,0.0004491,0.00006154121,0.0001426761],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005347241,0.00004645045,0.0001862882,0.00001201489,0.00001735922,0.000001810159,0.00003623031,0.00005150589,0.9874505,0.00002793932,0.008790595,0.003325817],"study_design_scores_gemma":[0.0003097005,0.0001933232,0.0004771554,0.00001093572,0.000006515845,0.000007354347,0.00003709226,0.0002133718,0.9565434,0.00001786201,0.04197599,0.0002072982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914343,0.0001105337,0.0003325466,0.0002611756,0.0001099255,0.000124529,0.00004108417,0.00002751706,0.007558432],"genre_scores_gemma":[0.9882535,0.00001758712,0.0003174923,0.0005620999,0.0001963635,0.000003972924,0.0007373001,0.0000332087,0.009878494],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0331854,"threshold_uncertainty_score":0.5915182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003772687685552496,"score_gpt":0.2161273357677151,"score_spread":0.2123546480821626,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}