{"id":"W2981663786","doi":"10.7554/elife.51230","title":"The human coronavirus HCoV-229E S-protein structure and receptor binding","year":2019,"lang":"en","type":"article","venue":"eLife","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":239,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; Canada Research Chairs; Institut National de la Recherche Scientifique; University of Toronto","funders":"Canadian Institutes of Health Research; Argonne National Laboratory; Canada Research Chairs; Canadian Light Source","keywords":"Coronavirus; Protein subunit; Chemistry; Protein structure; Biology; Cell biology; Computational biology; Crystallography; Biophysics; Biochemistry; Coronavirus disease 2019 (COVID-19)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005219534,0.000109149,0.0001044427,0.00008499993,0.0001903229,0.0002054934,0.00009517655,0.0001998272,0.001493225],"category_scores_gemma":[0.0001175908,0.00006008803,0.0001347358,0.00008272829,0.000120949,0.000105743,0.0001549026,0.000148184,0.0003687007],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003949307,"about_ca_system_score_gemma":0.0003325983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005262524,"about_ca_topic_score_gemma":0.00653362,"domain_scores_codex":[0.999947,0.000006315616,0.000002422625,0.000008342204,0.00002177864,0.00001417472],"domain_scores_gemma":[0.9999782,0.000002282091,0.00000483162,0.000002277169,0.000004041762,0.000008326791],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002648419,0.0000391878,0.006941771,0.0001215638,0.00002109573,0.0005644839,0.0001079381,0.0007978519,0.9718947,0.002887263,0.001556638,0.01480266],"study_design_scores_gemma":[0.0001419427,0.0008547507,0.2707767,0.00008095006,0.00005057379,0.004357813,0.0007812114,0.01031508,0.5983874,0.00401393,0.1101994,0.00004023217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9832754,0.004017814,0.001523054,0.0004556389,0.00002920627,0.00001898689,0.0004463699,0.00005489661,0.01017862],"genre_scores_gemma":[0.9922208,0.001472631,0.001256761,0.0001055516,0.00001272088,0.000005699797,0.0009315718,0.000003802928,0.003990408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005262524,"threshold_uncertainty_score":0.01046377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04142393679896621,"score_gpt":0.3564526433668104,"score_spread":0.3150287065678442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}