{"id":"W2981768909","doi":"10.1016/j.isci.2019.10.032","title":"Plant-Derived Exosomal Nanoparticles Inhibit Pathogenicity of Porphyromonas gingivalis","year":2019,"lang":"en","type":"article","venue":"iScience","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":214,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Center for Complementary and Integrative Health; National Institute of Dental and Craniofacial Research; National Institute on Alcohol Abuse and Alcoholism; National Institute of General Medical Sciences; Royal College of Surgeons of England; National Institutes of Health; M.S.I. Foundation","keywords":"Porphyromonas gingivalis; Exosome; Microvesicles; Chemistry; Microbiology; Phosphatidic acid; Pathogen; Hemin; Periodontitis; Pathogenic bacteria; Bacteria; Biology; Biochemistry; microRNA; Heme; Phospholipid; Medicine; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017852,0.0001012235,0.0001042429,0.00002617907,0.00004227815,0.00001477034,0.000322882,0.00005856101,0.00004948441],"category_scores_gemma":[0.00007278418,0.00009522989,0.00007386822,0.0001157198,0.000200309,0.000009123502,0.0001900841,0.00004255627,0.00004073971],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006666407,"about_ca_system_score_gemma":0.00007814495,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001262088,"about_ca_topic_score_gemma":0.000004143838,"domain_scores_codex":[0.9990014,0.00004108224,0.0001779462,0.0003378453,0.0002079575,0.0002337591],"domain_scores_gemma":[0.9993375,0.00001024823,0.00009229237,0.0004179827,0.00004848669,0.00009350572],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000312956,0.00005951321,0.01722759,0.00001324485,0.000006301766,0.000006620356,0.00005228182,0.00005535412,0.9816685,0.0001979437,0.0001289048,0.0005524946],"study_design_scores_gemma":[0.0002290286,0.000128385,0.01548387,0.00001255184,0.000007646187,0.00001122118,0.00005459101,0.0001624228,0.9830303,0.0001516269,0.0006000903,0.0001283133],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979008,0.000819419,0.0001523118,0.00005184092,0.0001077332,0.0001305038,0.00005413037,0.00001177316,0.0007714179],"genre_scores_gemma":[0.9987466,0.00002017669,0.0007716546,0.0001396271,0.00003831109,0.000004156105,0.00001919771,0.00001009986,0.0002501969],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001743718,"threshold_uncertainty_score":0.3883362,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009014176009265703,"score_gpt":0.2246922330314162,"score_spread":0.2156780570221505,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}