{"id":"W2981784436","doi":"10.1039/c9ob02079a","title":"Synthesis of defined mono-de-<i>N</i>-acetylated β-(1→6)-<i>N</i>-acetyl-<scp>d</scp>-glucosamine oligosaccharides to characterize PgaB hydrolase activity","year":2019,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; Hospital for Sick Children; University of Toronto; Toronto Public Health","funders":"Canadian Glycomics Network; Institute of Infection and Immunity; Canadian Institutes of Health Research; Canada Research Chairs; Canada Foundation for Innovation; Ontario Research Foundation","keywords":"Acetylation; Glucosamine; Hydrolysis; Chemistry; Stereochemistry; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001272862,0.000498711,0.0002234125,0.0001559221,0.0001002077,0.0002192584,0.0001929405,0.0002173207,0.0005882675],"category_scores_gemma":[0.0001840127,0.0000995626,0.000265478,0.0002295993,0.0001377514,0.000228129,0.0001815581,0.0004859878,0.0003627102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00020639,"about_ca_system_score_gemma":0.0003412467,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007246552,"about_ca_topic_score_gemma":0.001013111,"domain_scores_codex":[0.9998815,0.00001459114,0.00001066652,0.00002716843,0.00003764338,0.00002850537],"domain_scores_gemma":[0.9998456,0.00002193518,0.00003886522,0.00001383165,0.00003410128,0.00004563007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001556571,0.0000136529,0.00006228998,0.00001667513,0.000002377478,0.00002230765,0.000007982262,0.00007300857,0.998807,0.00004061947,0.000009632046,0.0009289288],"study_design_scores_gemma":[0.00000198308,0.0001061111,0.0005856203,0.000002454829,0.000005380371,0.0000624276,0.00001069494,0.0003461847,0.9981672,0.00002374074,0.0006846517,0.000003629227],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.954757,0.001348656,0.03994427,0.00008869759,0.00004819682,0.0001504595,0.001189827,0.0001198589,0.002353014],"genre_scores_gemma":[0.9535469,0.001132025,0.03965027,0.00009657378,0.00001361069,0.00007957287,0.002131983,0.0000652388,0.003283773],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007246552,"threshold_uncertainty_score":0.001967967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006724010861358156,"score_gpt":0.1969594485267334,"score_spread":0.1902354376653752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}