{"id":"W2981784436","doi":"10.1039/c9ob02079a","title":"Synthesis of defined mono-de-<i>N</i>-acetylated β-(1→6)-<i>N</i>-acetyl-<scp>d</scp>-glucosamine oligosaccharides to characterize PgaB hydrolase activity","year":2019,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; Hospital for Sick Children; University of Toronto; Toronto Public Health","funders":"Canadian Glycomics Network; Institute of Infection and Immunity; Canadian Institutes of Health Research; Canada Research Chairs; Canada Foundation for Innovation; Ontario Research Foundation","keywords":"Acetylation; Glucosamine; Hydrolysis; Chemistry; Stereochemistry; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004215028,0.0009465837,0.001243452,0.00009753436,0.0001445513,0.0001275349,0.001227645,0.0008428894,0.003512123],"category_scores_gemma":[0.001717066,0.001062737,0.0005722443,0.0009357554,0.0001794431,0.0002048009,0.0005000134,0.0005964095,0.0003107711],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004062419,"about_ca_system_score_gemma":0.000398091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009742577,"about_ca_topic_score_gemma":0.000002519117,"domain_scores_codex":[0.9957713,0.000065657,0.0008807693,0.001365264,0.0007035216,0.001213483],"domain_scores_gemma":[0.9957526,0.000589602,0.0005924291,0.002117709,0.0002162881,0.0007314076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001417638,0.0004610762,0.0005870197,0.001450207,0.0003585285,0.0001022054,0.0002051931,0.000003747561,0.9956893,0.000003431534,0.0002513907,0.0007461505],"study_design_scores_gemma":[0.0008468075,0.00003852485,0.0001524584,0.0003658967,0.0002388306,0.0001492501,0.0002466124,0.000323631,0.9939848,0.00001759993,0.003066547,0.0005691121],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9830453,0.0001953163,0.0007402668,0.0002541617,0.00008817911,0.000246744,0.0004310354,0.000338992,0.01465996],"genre_scores_gemma":[0.9954575,0.0001152664,0.0003669141,0.0001544758,0.0001750427,0.0001054702,0.0001848138,0.0002187976,0.003221691],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01241218,"threshold_uncertainty_score":0.9991823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006724010861358156,"score_gpt":0.1969594485267334,"score_spread":0.1902354376653752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}