{"id":"W2981820005","doi":"10.21926/obm.genet.1904097","title":"Optimizing Phage Translation Initiation","year":2019,"lang":"en","type":"article","venue":"OBM Genetics","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Eukaryotic translation; Start codon; Protein biosynthesis; Translation (biology); Computational biology; Limiting; Transfer RNA; Biology; Genetics; Gene; RNA; Messenger RNA; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008409839,0.0007563222,0.0007578892,0.0004375029,0.0004466988,0.001256434,0.0003724157,0.0006624755,0.001880739],"category_scores_gemma":[0.001207176,0.0003813292,0.0005332253,0.0004994075,0.0003486787,0.0006011646,0.0006990749,0.00166995,0.002355898],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001048098,"about_ca_system_score_gemma":0.0009694693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005589051,"about_ca_topic_score_gemma":0.00133224,"domain_scores_codex":[0.9992593,0.0001196506,0.00008491657,0.00019722,0.0001966983,0.0001422267],"domain_scores_gemma":[0.9995315,0.000151229,0.00009054122,0.00003844462,0.0001323737,0.00005585728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001078886,0.00004169185,0.000383546,0.0006055936,0.00001013381,0.00007106362,0.00009108752,0.001087006,0.9799985,0.001523511,0.0008186612,0.01526122],"study_design_scores_gemma":[0.00001419112,0.000196733,0.0005873461,0.00007554587,0.00002207132,0.0001019852,0.00005545517,0.003397589,0.9695114,0.0004444973,0.02556637,0.00002684539],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7176744,0.03100954,0.2130413,0.001573768,0.001521527,0.000587894,0.002236143,0.00311044,0.02924493],"genre_scores_gemma":[0.8207015,0.01530365,0.147188,0.0007471627,0.0001269904,0.0003745122,0.003634193,0.001088121,0.01083575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001880739,"threshold_uncertainty_score":0.007604539,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01736702007806277,"score_gpt":0.2432110514948809,"score_spread":0.2258440314168181,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}