{"id":"W2981827178","doi":"10.1093/ofid/ofz360.729","title":"661. Ibalizumab Efficacy and Safety Through 48 Weeks of Treatment: Results of an Expanded Access Protocol (TMB-311)","year":2019,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Theratechnologies (Canada)","funders":"Samsung","keywords":"Medicine; Tolerability; Regimen; Viral load; Internal medicine; Cohort; Human immunodeficiency virus (HIV); Adverse effect; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001026764,0.0002444132,0.0005303036,0.00008473341,0.0001900691,0.00005782403,0.0003572082,0.0001290653,0.0007342907],"category_scores_gemma":[0.00008329519,0.0001783369,0.0001050878,0.0001532246,0.0002287125,0.000655699,0.0003648963,0.00008332344,0.0002062807],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001052427,"about_ca_system_score_gemma":0.0002290428,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00271442,"about_ca_topic_score_gemma":0.0002796152,"domain_scores_codex":[0.9983979,0.0002849853,0.0004177119,0.0003923515,0.00005961833,0.0004474689],"domain_scores_gemma":[0.9988344,0.0001835575,0.0002452849,0.000561927,0.00008747177,0.00008737647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.04600398,0.01887432,0.8321776,0.000428661,0.003110916,0.00002625656,0.001801216,0.00004857442,0.009294771,0.002656701,0.006836545,0.07874043],"study_design_scores_gemma":[0.182904,0.0353415,0.5095122,0.0005057396,0.0005478113,0.0001578799,0.00105715,0.000008866075,0.1222406,0.001968079,0.1446702,0.001086036],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8959137,0.0002973464,0.000006351488,0.00009978972,0.0001401932,0.05634612,0.001999462,0.00006355959,0.04513344],"genre_scores_gemma":[0.986957,0.00006308127,0.00001302299,0.00002633898,0.000008962496,0.01048019,0.0006608586,0.00002102368,0.001769492],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3226655,"threshold_uncertainty_score":0.8039969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02141321896594533,"score_gpt":0.3497568800188321,"score_spread":0.3283436610528868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}