{"id":"W2981840909","doi":"10.1002/stem.3092","title":"Dynamic regulation of connexins in stem cell pluripotency","year":2019,"lang":"en","type":"article","venue":"Stem Cells","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland; Western University","funders":"Canadian Institutes of Health Research","keywords":"Induced pluripotent stem cell; Biology; Stem cell; Cell biology; Cell potency; Connexin; Induced stem cells; Cellular differentiation; Embryoid body; Embryonic stem cell; Adult stem cell; Gap junction; Genetics; Intracellular; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001369378,0.0001095315,0.0001712384,0.0000568772,0.00001162515,0.00000398144,0.0001280138,0.0001643013,0.00008338683],"category_scores_gemma":[7.994418e-7,0.000103592,0.00006748598,0.00007443935,0.00003349746,0.000002317508,0.00006141142,0.00005784884,0.00005910374],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001279098,"about_ca_system_score_gemma":0.00004385272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002190953,"about_ca_topic_score_gemma":0.00006996584,"domain_scores_codex":[0.9991754,0.00006233922,0.0002461314,0.0002778212,0.00006111604,0.000177219],"domain_scores_gemma":[0.999467,0.00001402692,0.0001076913,0.0003390578,0.00004221909,0.00002999368],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005669998,0.00004113744,0.003178519,0.00005108833,0.000008027454,9.096181e-7,0.00005857199,0.0001401588,0.9929,0.0001308449,0.00007793815,0.003356095],"study_design_scores_gemma":[0.0009970677,0.0004610936,0.009209422,0.0000257716,0.000007884575,0.000003342889,0.0003059132,0.0007304281,0.9669448,0.00004733014,0.02105212,0.000214859],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932902,0.0007231978,0.00008985815,0.00002586384,0.0002292337,0.0002331804,0.00001918978,0.000005511214,0.005383778],"genre_scores_gemma":[0.9915047,0.0001146495,0.00007480993,0.000043019,0.00001957066,0.000004447358,0.00003239197,0.00001356416,0.008192806],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02595525,"threshold_uncertainty_score":0.4224359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004693713340745333,"score_gpt":0.2017491494663429,"score_spread":0.1970554361255975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}