{"id":"W2981870909","doi":"10.1371/journal.pone.0224206","title":"Myomesin is part of an integrity pathway that responds to sarcomere damage and disease","year":2019,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"MacEwan University; University of Toronto; University of Alberta; University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Sarcomere; Titin; Myosin; Cell biology; Myocyte; Myofibril; Biology; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000195745,0.0003921377,0.0002494622,0.0003906837,0.0004344702,0.0003126572,0.0001496877,0.0005118204,0.001865914],"category_scores_gemma":[0.0001622762,0.0001606901,0.0001933885,0.0001701871,0.0003357193,0.0003212742,0.0004168261,0.0005733887,0.0004608835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002682991,"about_ca_system_score_gemma":0.000269521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003725649,"about_ca_topic_score_gemma":0.0006108982,"domain_scores_codex":[0.9998322,0.00001671731,0.000008950635,0.0000673582,0.00005137729,0.00002339684],"domain_scores_gemma":[0.9998742,0.00001076578,0.00004291293,0.000009837056,0.00001721743,0.0000450248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008171962,0.00000544565,0.000793062,0.00004052288,0.000004793992,0.000126348,0.00002343818,0.00002828543,0.9964215,0.0001807584,0.00009091089,0.002203376],"study_design_scores_gemma":[0.00002431056,0.0004258513,0.1454374,0.00004634097,0.00004659654,0.002769979,0.0001582077,0.001107729,0.8277584,0.0006048428,0.02159089,0.00002948464],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9595166,0.01026711,0.02128004,0.0005594219,0.0002290498,0.00009960935,0.002448274,0.0006074199,0.004992347],"genre_scores_gemma":[0.9806954,0.002543663,0.008037242,0.0002155791,0.00002957705,0.00007724848,0.001084264,0.00006159784,0.007255384],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001865914,"threshold_uncertainty_score":0.006242156,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06652208758375622,"score_gpt":0.2722114479537068,"score_spread":0.2056893603699506,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}