{"id":"W2981881162","doi":"10.3390/molecules24213846","title":"Catalyst-Free Synthesis of Polysubstituted 5-Acylamino-1,3-Thiazoles via Hantzsch Cyclization of α-Chloroglycinates","year":2019,"lang":"en","type":"article","venue":"Molecules","topic":"Sulfur-Based Synthesis Techniques","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Catalysis; Chemistry; Combinatorial chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000160846,0.0004714702,0.0002856574,0.000275698,0.000186807,0.0001856266,0.0003902222,0.0002863349,0.001952297],"category_scores_gemma":[0.0001367445,0.0001619264,0.0002614512,0.0002268144,0.0002298457,0.0002244228,0.000285396,0.0004918601,0.0006398009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003223544,"about_ca_system_score_gemma":0.0004949664,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008962012,"about_ca_topic_score_gemma":0.002671637,"domain_scores_codex":[0.9998426,0.0000191007,0.00001193682,0.0000249654,0.00004456552,0.00005678813],"domain_scores_gemma":[0.999938,0.000007570256,0.00001565442,0.000008235699,0.00001103763,0.00001948722],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008539085,0.0000359189,0.00008300798,0.000134449,0.00001584077,0.0002745997,0.00006389712,0.0004266195,0.9921132,0.001038752,0.000139513,0.005588782],"study_design_scores_gemma":[0.00003065032,0.0003635053,0.0008286015,0.000006834343,0.00001614401,0.0002241462,0.00002021144,0.0005701204,0.9929495,0.0001047773,0.004871084,0.00001445458],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9559808,0.002674794,0.02751068,0.0001784801,0.0001056541,0.0002043668,0.0007990302,0.0003989031,0.01214727],"genre_scores_gemma":[0.9826842,0.002297854,0.009239236,0.00004544264,0.00002019969,0.00006930232,0.0005070687,0.00005799267,0.00507866],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001952297,"threshold_uncertainty_score":0.00653106,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005413179546295302,"score_gpt":0.2097744576077659,"score_spread":0.2043612780614706,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}