{"id":"W2981926059","doi":"10.1002/cyto.a.23919","title":"Single Cell Phenotypic Profiling of 27 DLBCL Cases Reveals Marked Intertumoral and Intratumoral Heterogeneity","year":2019,"lang":"en","type":"article","venue":"Cytometry Part A","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute; BC Cancer Agency","funders":"Japan Society for the Promotion of Science; Genome Canada; Terry Fox Research Institute; Leukemia and Lymphoma Society","keywords":"Phenotype; Mass cytometry; Biology; Lymphoma; Genetic heterogeneity; Diffuse large B-cell lymphoma; Cancer research; Context (archaeology); Pathology; Immunology; Genetics; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001516902,0.000185672,0.0004891761,0.0001514391,0.00002849067,0.00002181956,0.00005835034,0.00006854336,0.0001311298],"category_scores_gemma":[0.00007628578,0.0001480286,0.0001036626,0.0002535543,0.0000715779,0.00007599185,0.00007816974,0.00007705757,0.0000686331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009841539,"about_ca_system_score_gemma":0.00004629092,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001847259,"about_ca_topic_score_gemma":0.000003191113,"domain_scores_codex":[0.9988627,0.00004909421,0.0003228464,0.0003191969,0.0001854707,0.0002606271],"domain_scores_gemma":[0.9991878,0.0001322617,0.0001301818,0.0003236078,0.00006938919,0.0001567362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002985033,0.001041883,0.9438163,0.0004384116,0.00008020551,0.0001499802,0.00006408651,3.439891e-7,0.05204502,0.00003120599,0.0004751791,0.001558892],"study_design_scores_gemma":[0.005127751,0.001957754,0.374822,0.0004672502,0.0002305184,0.0003346515,0.0002075397,0.00007192147,0.615539,0.00002933687,0.0009647377,0.0002474923],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953157,0.001545454,0.000004807638,0.00006688064,0.0002735143,0.0004975273,0.00003101879,0.00003491753,0.002230222],"genre_scores_gemma":[0.9982541,0.00005565888,0.0008931864,0.0001624875,0.00008273682,0.00001938648,0.00004178908,0.00002125889,0.0004693743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5689943,"threshold_uncertainty_score":0.6036433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02843418346740925,"score_gpt":0.2735828115848192,"score_spread":0.2451486281174099,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}