{"id":"W2982015658","doi":"10.1111/dom.13901","title":"Similar glycaemic control and less hypoglycaemia during active titration after insulin initiation with glargine 300 units/mL and degludec 100 units/mL: A subanalysis of the BRIGHT study","year":2019,"lang":"en","type":"article","venue":"Diabetes Obesity and Metabolism","topic":"Diabetes Management and Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Toronto","funders":"Genentech; HLS Therapeutics; Ipsen; Novo Nordisk; Intarcia Therapeutics; Sanofi; GlaxoSmithKline; Roche Diabetes Care; Servier; Pfizer; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Insulin degludec; Insulin glargine; Titration; Insulin; Medicine; Hypoglycemia; Internal medicine; Endocrinology; Chemistry; Inorganic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005902431,0.0004940475,0.001743492,0.0002788039,0.0002630878,0.0009722706,0.0004566257,0.0009027778,0.001970164],"category_scores_gemma":[0.002979467,0.0003160799,0.002057658,0.0002737227,0.000605526,0.0006786456,0.0004401816,0.001123636,0.0003082346],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003209656,"about_ca_system_score_gemma":0.0005317737,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003109435,"about_ca_topic_score_gemma":0.0004635374,"domain_scores_codex":[0.9973218,0.001560597,0.0001904694,0.000298776,0.0003639745,0.0002644307],"domain_scores_gemma":[0.9968402,0.001011778,0.0009926995,0.0004121775,0.0001956528,0.0005474582],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8593372,0.00595013,0.0809806,0.001092036,0.006597685,0.0001424844,0.0002291006,0.000211474,0.01138181,0.0001202499,0.0007428812,0.03321434],"study_design_scores_gemma":[0.173942,0.3282506,0.4844362,0.0001646662,0.006707505,0.0003656257,0.0002731588,0.0005877779,0.00240649,0.0002704966,0.002504763,0.00009066594],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964672,0.002104209,0.000212845,0.00006749562,0.00004250372,0.0002139996,0.0001888911,0.00001234026,0.0006903988],"genre_scores_gemma":[0.9981591,0.0003951445,0.0002476244,0.0002727117,0.00008262946,0.0001051215,0.0003918495,0.000006553578,0.0003393211],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005902431,"threshold_uncertainty_score":0.03121537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008804360340932764,"score_gpt":0.2140965924144282,"score_spread":0.2052922320734955,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}