{"id":"W2982028489","doi":"10.1007/s12325-019-01123-0","title":"Efficacy and Safety of 8 Weeks of Glecaprevir/Pibrentasvir in Treatment-Naïve, HCV-Infected Patients with APRI ≤ 1 in a Single-Arm, Open-Label, Multicenter Study","year":2019,"lang":"en","type":"article","venue":"Advances in Therapy","topic":"Hepatitis C virus research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Liver Centre","funders":"AbbVie","keywords":"Medicine; Internal medicine; Regimen; Gastroenterology; Cirrhosis; Adverse effect; Hepatitis C virus; Hepatitis C; Viral load; Immunology; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00296324,0.001320253,0.001514529,0.0002870538,0.0003312385,0.0008522772,0.0006308748,0.001030579,0.001825521],"category_scores_gemma":[0.002067133,0.0006037436,0.001369914,0.000346287,0.000651411,0.0009730874,0.0003472323,0.001605571,0.000510043],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006095948,"about_ca_system_score_gemma":0.0008986082,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005462502,"about_ca_topic_score_gemma":0.0009151938,"domain_scores_codex":[0.9987895,0.0006930671,0.00007843236,0.0002103869,0.000128378,0.0001003043],"domain_scores_gemma":[0.9979432,0.0002841959,0.0007087014,0.0002534648,0.0001318781,0.000678552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8688099,0.03786647,0.03880186,0.0003839255,0.002487502,0.0001122588,0.0003012542,0.0008608889,0.01081817,0.00006666613,0.0007041162,0.0387869],"study_design_scores_gemma":[0.4402015,0.4419008,0.111417,0.00004368236,0.001109451,0.000273553,0.0001059381,0.002225692,0.001871843,0.000108253,0.0006712197,0.00007115281],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988728,0.0003580984,0.0001015314,0.00004732085,0.0000145159,0.0002139748,0.0001940795,0.00001393396,0.00018364],"genre_scores_gemma":[0.9983274,0.0002037679,0.00030625,0.00011763,0.00005392083,0.0002881308,0.0004575302,0.000004904934,0.0002404032],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00296324,"threshold_uncertainty_score":0.01567131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03369446746467003,"score_gpt":0.3613446588565933,"score_spread":0.3276501913919233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}