{"id":"W2982063399","doi":"10.1016/j.jtho.2019.08.527","title":"MA04.10 Development and Validation of a Gene Expression-Based Prognostic Signature in Early-Stage Squamous Cell Carcinoma of the Lung","year":2019,"lang":"en","type":"article","venue":"Journal of Thoracic Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Stage (stratigraphy); Gene signature; Oncology; Basal cell; Lung; Signature (topology); Squamous-cell carcinoma of the lung; Gene expression; Internal medicine; Gene; Cancer research; Pathology; Genetics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001482034,0.0004826721,0.0005279059,0.001292062,0.0004108137,0.001500659,0.0005607749,0.0006995042,0.001738356],"category_scores_gemma":[0.001617591,0.0002766618,0.0003471624,0.000956369,0.0003037624,0.0003043114,0.0005549275,0.0006614459,0.0009003227],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000555656,"about_ca_system_score_gemma":0.0008487626,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001047366,"about_ca_topic_score_gemma":0.002024034,"domain_scores_codex":[0.9992162,0.0001467786,0.00007105533,0.000156357,0.0002544715,0.0001551056],"domain_scores_gemma":[0.9993913,0.0001457714,0.0001081692,0.00006125164,0.0002052257,0.00008824694],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002370127,0.0005580086,0.4148711,0.0003411871,0.0003600768,0.0005566606,0.000219962,0.00315035,0.4565225,0.000830862,0.005921792,0.1142973],"study_design_scores_gemma":[0.0003579229,0.004067834,0.6211761,0.0001680363,0.00101914,0.004938257,0.0005459885,0.04793668,0.2823541,0.001302749,0.0360274,0.0001059091],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9868014,0.002004927,0.004051273,0.0005631685,0.0001405171,0.0001182291,0.002896941,0.0001821209,0.003241404],"genre_scores_gemma":[0.9842292,0.0004997837,0.007248625,0.0002284319,0.00005567739,0.0001330631,0.005393236,0.00004899564,0.002162978],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001738356,"threshold_uncertainty_score":0.007837892,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01271855469897577,"score_gpt":0.3540706444717813,"score_spread":0.3413520897728056,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}