{"id":"W2982168455","doi":"10.1242/jeb.211623","title":"Malpighian tubules of caterpillars: blending RNAseq and physiology to reveal regional functional diversity and novel epithelial ion transport control mechanisms","year":2019,"lang":"en","type":"article","venue":"Journal of Experimental Biology","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Reabsorption; Malpighian tubule system; Biology; Ion channel; Septate junctions; Ion transporter; Cell biology; Hindgut; Tubule; Receptor; Secretion; Renal physiology; Insect; Anatomy; Midgut; Biochemistry; Larva; Kidney; Endocrinology; Botany; Intracellular","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001064839,0.0001592259,0.0001498939,0.0002085822,0.0001582999,0.0002346328,0.0001336478,0.0002153379,0.0005800804],"category_scores_gemma":[0.00006662815,0.0001077992,0.0001722694,0.0001428603,0.0002435394,0.0004748959,0.0001898187,0.0002647652,0.0001377208],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001993328,"about_ca_system_score_gemma":0.0001065704,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007446756,"about_ca_topic_score_gemma":0.001279975,"domain_scores_codex":[0.9999601,0.000004600113,0.000002126216,0.00001654678,0.000007450141,0.000009203671],"domain_scores_gemma":[0.9999638,0.000007319515,0.00001087634,0.000004597376,0.000005747433,0.000007736229],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002069354,0.000001844439,0.0004415404,0.00001748767,0.000002131364,0.00002438226,0.00001638731,0.00002951035,0.9985416,0.00005635967,0.000005906513,0.0008421161],"study_design_scores_gemma":[0.00001605576,0.0004173942,0.2284577,0.00002039881,0.00004299065,0.001137407,0.0003689936,0.004706187,0.7602141,0.0006170499,0.003977716,0.00002402403],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990352,0.001678554,0.00684539,0.000111599,0.000009170089,0.00001633932,0.0002611884,0.00006316829,0.0006625459],"genre_scores_gemma":[0.9921595,0.001009721,0.0052716,0.00008409721,0.000009804773,0.00002708747,0.0002871237,0.00002135072,0.001129673],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007446756,"threshold_uncertainty_score":0.001940548,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03547672228407781,"score_gpt":0.2770756193387369,"score_spread":0.2415988970546591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}