{"id":"W2982198004","doi":"10.1038/s41388-019-1068-z","title":"GGA3-mediated recycling of the RET receptor tyrosine kinase contributes to cell migration and invasion","year":2019,"lang":"en","type":"article","venue":"Oncogene","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Metropolitan University; Queen's University","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Cell biology; Endosome; Biology; Receptor tyrosine kinase; Signal transducing adaptor protein; Cell migration; Receptor; Protein kinase B; Kinase; Cell; Cancer research; Signal transduction; Biochemistry; Intracellular","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001370299,0.00007376289,0.00009646661,0.00002055054,0.00003088951,0.000006649094,0.00006826712,0.0001020544,0.00002310368],"category_scores_gemma":[0.00003550354,0.00005667292,0.00004316992,0.00008864384,0.00002098296,0.000002149328,0.00003222043,0.00003828531,0.000009622659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007832528,"about_ca_system_score_gemma":0.00002720743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003690528,"about_ca_topic_score_gemma":0.0001391184,"domain_scores_codex":[0.9994884,0.00002898517,0.0001468093,0.000173952,0.00007275508,0.0000891703],"domain_scores_gemma":[0.999633,0.000009146233,0.0000614544,0.0001971662,0.0000634047,0.00003588706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009643307,0.00002251624,0.03072852,0.00001902506,0.000006863435,1.575762e-7,0.00003394201,0.00001471971,0.9685982,0.000008665048,0.0001658218,0.0003051377],"study_design_scores_gemma":[0.0004575093,0.0001353063,0.005041214,0.00002863039,0.00001280556,4.807878e-7,0.00002377938,0.00003877087,0.9389371,0.00000943012,0.05524671,0.00006825462],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997438,0.0008658451,0.0006367181,0.0003880266,0.0001669986,0.0002456,0.00003041948,0.000003980688,0.0002243692],"genre_scores_gemma":[0.9973891,0.0003507719,0.0002020771,0.0001701008,0.00004809392,0.000004590266,0.001212394,0.000009524144,0.0006133813],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05508089,"threshold_uncertainty_score":0.2311055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005861326088087928,"score_gpt":0.1993823746219961,"score_spread":0.1935210485339081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}