{"id":"W2982435333","doi":"10.3390/cells8111341","title":"MLL-Rearranged Acute Leukemia with t(4;11)(q21;q23)—Current Treatment Options. Is There a Role for CAR-T Cell Therapy?","year":2019,"lang":"en","type":"review","venue":"Cells","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"AXYS Technologies (Canada)","funders":"","keywords":"Leukemia; Chromosomal translocation; Myeloid leukemia; Acute leukemia; Medicine; Oncology; Cancer research; Fusion gene; Internal medicine; Immunology; Biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004083867,0.0006025034,0.001270852,0.00148541,0.0002358694,0.0008616894,0.00082695,0.0009870393,0.003679267],"category_scores_gemma":[0.0005614432,0.000214858,0.0004289199,0.001564537,0.0003307008,0.0012666,0.0005754963,0.001596066,0.002487074],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005110094,"about_ca_system_score_gemma":0.0007838286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007757776,"about_ca_topic_score_gemma":0.001389756,"domain_scores_codex":[0.9998651,0.00002274851,0.00002181165,0.00002763358,0.00004807334,0.00001475235],"domain_scores_gemma":[0.9997889,0.00009942453,0.00002979822,0.000005756773,0.00005087202,0.00002523107],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005578565,0.00004375582,0.00009683961,0.01110167,0.00005493477,0.0001707986,0.00003859957,0.0002375096,0.001045961,0.001618783,0.0313758,0.9541596],"study_design_scores_gemma":[0.00001705036,0.00008725667,0.0004565398,0.003176447,0.0001165469,0.001322265,0.00005514083,0.00007415695,0.0003042158,0.001361295,0.9930153,0.00001372734],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008561636,0.9984856,0.0001095173,0.0003705598,0.0001575988,0.000004526281,0.0000242089,0.00001250304,0.0007498657],"genre_scores_gemma":[0.0004036425,0.9986668,0.0001518537,0.0002787852,0.0001221379,0.000007110878,0.00003757356,0.000001778006,0.0003302955],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003679267,"threshold_uncertainty_score":0.01230842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08670962398240774,"score_gpt":0.3794430066666013,"score_spread":0.2927333826841936,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}