{"id":"W2982469782","doi":"10.1002/cbin.11258","title":"PTEN promotes intervertebral disc degeneration by regulating nucleus pulposus cell behaviors","year":2019,"lang":"en","type":"article","venue":"Cell Biology International","topic":"Spine and Intervertebral Disc Pathology","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"National Natural Science Foundation of China","keywords":"PTEN; Tensin; PI3K/AKT/mTOR pathway; Protein kinase B; Cancer research; Cell biology; Biology; Signal transduction; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001226553,0.0002125484,0.0002853622,0.0001383395,0.00004733263,0.00002654648,0.0002516567,0.0002395292,0.004263514],"category_scores_gemma":[0.00003915321,0.0001781581,0.0001812264,0.00007433838,0.0000946633,0.0001527234,0.000132953,0.0002539399,0.0007493387],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009951776,"about_ca_system_score_gemma":0.00003943573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005385265,"about_ca_topic_score_gemma":0.000007492747,"domain_scores_codex":[0.9986203,0.00006193847,0.0004254542,0.00046228,0.0001372597,0.0002927702],"domain_scores_gemma":[0.9993395,0.00001153338,0.0001704727,0.0002542142,0.0001322445,0.00009208523],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003864733,0.0003032701,0.07300396,0.00002439191,0.00003627528,0.00001138762,0.0001197517,0.000003294556,0.9165733,0.0003970621,0.007090205,0.002398387],"study_design_scores_gemma":[0.003765494,0.00182304,0.03945446,0.00008346126,0.0001041785,0.000140178,0.0002373185,0.007371115,0.9406655,0.0002004659,0.005709475,0.0004453313],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9591614,0.0001607747,0.0005993217,0.0009682801,0.001351548,0.0003229623,0.00007650943,0.0000760571,0.03728312],"genre_scores_gemma":[0.980569,0.0000123465,0.001853474,0.0007717382,0.0002288983,0.00003051795,0.001645556,0.00002927967,0.0148592],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0335495,"threshold_uncertainty_score":0.9966467,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01073922182401324,"score_gpt":0.2699507235074394,"score_spread":0.2592115016834261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}