{"id":"W2982472170","doi":"10.3390/genes10110870","title":"Helicases FANCJ, RTEL1 and BLM Act on Guanine Quadruplex DNA in Vivo","year":2019,"lang":"en","type":"review","venue":"Genes","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"Canadian Institutes of Health Research","keywords":"Helicase; Telomere; Biology; Genome instability; Context (archaeology); Genome; DNA; Gene; Genetics; G-quadruplex; Cell biology; DNA damage; Computational biology; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003216913,0.0007424144,0.0007565042,0.002106097,0.0002299737,0.0007063911,0.0004777334,0.0006463625,0.002834834],"category_scores_gemma":[0.0004053836,0.0002320034,0.0002534128,0.001816992,0.0003294346,0.001014979,0.000450646,0.0009608787,0.002203933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000507453,"about_ca_system_score_gemma":0.0007650863,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007079783,"about_ca_topic_score_gemma":0.001294375,"domain_scores_codex":[0.9999095,0.00001227134,0.00001431375,0.00002089218,0.00003245599,0.0000105734],"domain_scores_gemma":[0.9998317,0.00007749358,0.00002873926,0.000004882062,0.00004089674,0.00001625755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005122268,0.00003087004,0.0001437701,0.01419683,0.00004429015,0.0001688137,0.00004776287,0.0002544664,0.003093353,0.004096588,0.0205611,0.9573109],"study_design_scores_gemma":[0.000004448324,0.00004009402,0.0004359586,0.001413284,0.0000369871,0.0006946792,0.00002819218,0.00003313862,0.0006223938,0.0009630998,0.9957191,0.000008476041],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001558891,0.9977866,0.0001356674,0.0002048604,0.0001822874,0.000003392181,0.0000208142,0.000008368214,0.001502019],"genre_scores_gemma":[0.0006340371,0.9979168,0.0002122134,0.0001341835,0.0001248373,0.000004958441,0.00003721833,0.000001637297,0.0009341115],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002834834,"threshold_uncertainty_score":0.009483457,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03301218235268946,"score_gpt":0.3152726227626693,"score_spread":0.2822604404099798,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}