{"id":"W2982480227","doi":"10.1039/c9an01869g","title":"Single point single-cell nanoparticle mediated pulsed laser optoporation","year":2019,"lang":"en","type":"article","venue":"The Analyst","topic":"Gold and Silver Nanoparticles Synthesis and Applications","field":"Materials Science","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Polytechnique Montréal","funders":"","keywords":"Laser; Nanoparticle; Microscopy; Pulsed laser; Fluorescence microscope; Materials science; Nanotechnology; Fluorescence; Membrane; Perforation; Live cell imaging; Single-cell analysis; Biophysics; Optics; Chemistry; Cell; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000226986,0.0003841408,0.0005179447,0.0001888099,0.0001776093,0.0004129353,0.0006370309,0.000619232,0.0007649634],"category_scores_gemma":[0.0001979268,0.0002176994,0.000245296,0.000153157,0.0004222263,0.0003954909,0.000467441,0.0007470602,0.0005345033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002797969,"about_ca_system_score_gemma":0.0002471949,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002629285,"about_ca_topic_score_gemma":0.0004668538,"domain_scores_codex":[0.999755,0.00002317703,0.0000139973,0.00008188151,0.0001018521,0.00002414898],"domain_scores_gemma":[0.9998133,0.0000692469,0.00003962433,0.00003422887,0.00002502559,0.00001864863],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000009210527,0.000006046878,0.00002252927,0.00002339461,0.00000157646,0.00002494983,0.00001364945,0.0001049621,0.9985456,0.0001662267,0.00002618805,0.001055737],"study_design_scores_gemma":[0.000001899206,0.00002201384,0.00009111638,9.21065e-7,0.000001877355,0.00006540192,0.000003647176,0.001458364,0.9974622,0.00003893587,0.0008507349,0.000002880406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7669362,0.001589325,0.2266452,0.0002058008,0.0001290153,0.0002131522,0.0004685877,0.0008647493,0.002947895],"genre_scores_gemma":[0.8535182,0.001348866,0.1394191,0.0000720272,0.00002374415,0.0002980745,0.000493716,0.0001223618,0.00470388],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007649634,"threshold_uncertainty_score":0.002559066,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01673705729145781,"score_gpt":0.2126190522619833,"score_spread":0.1958819949705255,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}