{"id":"W2982494927","doi":"10.3390/cells8111340","title":"A Low-Therapeutic Dose of Lithium Inhibits GSK3 and Enhances Myoblast Fusion in C2C12 Cells","year":2019,"lang":"en","type":"article","venue":"Cells","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sinai Health System; Lunenfeld-Tanenbaum Research Institute; Brock University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Myogenesis; C2C12; Myogenin; Lithium (medication); Chemistry; Myocyte; GSK3B; GSK-3; Myosin; Internal medicine; Phosphorylation; Endocrinology; Cell biology; Biochemistry; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003641099,0.0005869743,0.000845556,0.0004438712,0.0003904252,0.0003789309,0.0004406705,0.0005235493,0.001636387],"category_scores_gemma":[0.0001565314,0.0002031072,0.000730383,0.0005768079,0.0004218354,0.0002217728,0.0002768892,0.001106446,0.0005106708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006441459,"about_ca_system_score_gemma":0.0006165069,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003822043,"about_ca_topic_score_gemma":0.008686002,"domain_scores_codex":[0.9995008,0.00007396823,0.00009830423,0.00007245383,0.0001470284,0.000107456],"domain_scores_gemma":[0.9998224,0.00003310947,0.00004043285,0.00002256251,0.00002745586,0.00005414178],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003686936,0.0001348198,0.0001481333,0.0001232226,0.0000117297,0.00003833383,0.00004290929,0.00004270815,0.9975817,0.00004296293,0.0001441775,0.00132058],"study_design_scores_gemma":[0.00005692888,0.001187181,0.004236678,0.00001208603,0.00003027232,0.00007867822,0.00004311548,0.0005760969,0.9919234,0.00001372541,0.001834272,0.00000766152],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880654,0.004356658,0.002344436,0.0003286344,0.0001150129,0.0001062611,0.00137907,0.0003140355,0.00299064],"genre_scores_gemma":[0.9842684,0.002134054,0.005454636,0.0001799131,0.00003488194,0.000278129,0.002102847,0.00004809711,0.005498928],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003822043,"threshold_uncertainty_score":0.007599592,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004140655735834729,"score_gpt":0.2128741137710687,"score_spread":0.208733458035234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}