{"id":"W2982494927","doi":"10.3390/cells8111340","title":"A Low-Therapeutic Dose of Lithium Inhibits GSK3 and Enhances Myoblast Fusion in C2C12 Cells","year":2019,"lang":"en","type":"article","venue":"Cells","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sinai Health System; Lunenfeld-Tanenbaum Research Institute; Brock University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Myogenesis; C2C12; Myogenin; Lithium (medication); Chemistry; Myocyte; GSK3B; GSK-3; Myosin; Internal medicine; Phosphorylation; Endocrinology; Cell biology; Biochemistry; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008562506,0.0001040187,0.0001418723,0.00003501568,0.0000162887,0.000004478143,0.00008392827,0.0001413739,0.00006288553],"category_scores_gemma":[0.000004243217,0.00009501449,0.00003856008,0.00006057702,0.00006803637,0.000003505339,0.00007347172,0.0000669393,0.00003124706],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002638149,"about_ca_system_score_gemma":0.00002689098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001422625,"about_ca_topic_score_gemma":0.00002076708,"domain_scores_codex":[0.9993491,0.00004596065,0.000148826,0.0002491652,0.00004943127,0.0001575371],"domain_scores_gemma":[0.9996774,0.00001642583,0.00006108075,0.0001887521,0.00002218785,0.00003417831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001498295,0.00008979853,0.0007167851,0.00007954094,0.000008973734,3.725563e-7,0.0001215381,0.00003710355,0.9973062,0.00001710231,0.0001295452,0.001343211],"study_design_scores_gemma":[0.00061956,0.0002776601,0.003254229,0.00003205396,0.000004253385,4.514544e-7,0.0001002368,0.00002844438,0.9934868,0.0001150352,0.001969839,0.0001114232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968169,0.0009170753,0.00002282611,0.00002432431,0.0001427532,0.0001625456,0.000004448619,0.000003354216,0.001905827],"genre_scores_gemma":[0.9985808,0.000529354,0.000039486,0.0002224804,0.00002950999,0.000005021824,0.00001245989,0.000009084387,0.0005718042],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003819386,"threshold_uncertainty_score":0.3874578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004140655735834729,"score_gpt":0.2128741137710687,"score_spread":0.208733458035234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}