{"id":"W2982575013","doi":"10.1016/j.jad.2020.03.033","title":"The uterine-chemokine-brain axis: menstrual cycle-associated symptoms (MCAS) are in part mediated by CCL2, CCL5, CCL11, CXCL8 and CXCL10","year":2020,"lang":"en","type":"article","venue":"Journal of Affective Disorders","topic":"Menstrual Health and Disorders","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Chulalongkorn University","keywords":"CCL5; Menstrual cycle; Medicine; Chemokine; CCL11; CCL2; Internal medicine; Endocrinology; Immunology; Hormone; Inflammation; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008241676,0.000365063,0.0007927727,0.0001647063,0.0001971958,0.00005001919,0.000196284,0.0002228541,0.00005775185],"category_scores_gemma":[0.003322073,0.000264974,0.0001792263,0.0006977267,0.0002570181,0.0002067283,0.00007030656,0.0008754364,0.000008374067],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001811322,"about_ca_system_score_gemma":0.0002555308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000126631,"about_ca_topic_score_gemma":0.000635536,"domain_scores_codex":[0.9971595,0.0003447059,0.0008497315,0.0003517549,0.0006408119,0.0006534638],"domain_scores_gemma":[0.9971383,0.001025231,0.000745801,0.0001777222,0.0002278404,0.0006851593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.008424445,0.002354292,0.6211417,0.0009496526,0.001638242,0.0004955228,0.008902246,0.000108982,0.004109503,0.0002074095,0.2002402,0.1514278],"study_design_scores_gemma":[0.1015667,0.01768418,0.6416239,0.002146322,0.0006820665,0.0005366284,0.04234523,0.006687443,0.001252041,0.002301245,0.1809112,0.002263037],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9608577,0.002435749,0.00004070779,0.03474973,0.0003931495,0.00064398,0.00005597122,0.00003874766,0.0007842628],"genre_scores_gemma":[0.9933159,0.001516459,0.0000223964,0.004823151,0.000136203,0.00001974884,0.00002877812,0.00005025119,0.00008712253],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1491648,"threshold_uncertainty_score":0.9999803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008327058446539734,"score_gpt":0.274304608035326,"score_spread":0.2659775495887863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}