{"id":"W2982588758","doi":"10.1053/j.gastro.2019.10.023","title":"Interpreting Reported Risks Associated With Use of Proton Pump Inhibitors: Residual Confounding in a 10-Year Analysis of National Ambulatory Data","year":2019,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Gastroesophageal reflux and treatments","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Population Health Research Institute; Robarts Clinical Trials; University of Calgary","funders":"","keywords":"Medicine; Medical prescription; Observational study; Adverse effect; Scopus; Pharmacy; Proton-pump inhibitor; Ambulatory; Internal medicine; MEDLINE; Confounding; Randomized controlled trial; Placebo; Journal club; Family medicine; Intensive care medicine; Alternative medicine; Pharmacology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005919268,0.0001502977,0.0006800636,0.0006192639,0.00001310933,0.000007092427,0.0001137549,0.00009354162,0.0001486932],"category_scores_gemma":[0.0006584356,0.0001251445,0.00007747153,0.0004027527,0.0001077042,0.0001547983,0.0001359944,0.0001809207,0.000003606031],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001295153,"about_ca_system_score_gemma":0.00009480945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001301548,"about_ca_topic_score_gemma":0.0001535375,"domain_scores_codex":[0.9980776,0.0001684974,0.0006681375,0.0003964127,0.0004107314,0.0002786265],"domain_scores_gemma":[0.9984339,0.000129682,0.0006406681,0.0004737734,0.0002588787,0.00006304903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001518059,0.0003486481,0.9939421,0.0000343804,0.002635657,0.0001065919,0.0001149479,0.000203159,0.001040045,0.000004393321,0.00003620562,0.00001579256],"study_design_scores_gemma":[0.003326653,0.001589647,0.9917251,0.0001929956,0.0007367166,0.00001658403,0.00004666368,0.001807369,0.0005172326,0.000003151643,0.000006425763,0.00003139591],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990366,0.000003272922,0.00003260179,0.00003303207,0.00004191963,0.0005839175,0.0001413904,0.00001610175,0.0001112015],"genre_scores_gemma":[0.9983565,0.000001160581,0.0003940627,0.00006244351,0.00001421285,0.00001998464,0.001048875,0.00001586547,0.00008684978],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002216955,"threshold_uncertainty_score":0.5103245,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0895463048765225,"score_gpt":0.3532580019570364,"score_spread":0.263711697080514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}