{"id":"W2982674042","doi":"10.1016/j.scr.2019.101641","title":"Post-Passage rock inhibition induces cytoskeletal aberrations and apoptosis in Human embryonic stem cells","year":2019,"lang":"en","type":"article","venue":"Stem Cell Research","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Bone and Joint Health Institute; University of Calgary","funders":"National Key Research and Development Program of China; Canadian Institutes of Health Research","keywords":"Biology; Cell biology; Embryonic stem cell; Cytoskeleton; Anoikis; Matrigel; Actin; Microtubule; Stem cell; Apoptosis; Cell culture; Cell; Programmed cell death; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009449451,0.0002642169,0.000251683,0.0001564578,0.0001278143,0.0001884665,0.000146728,0.0001527223,0.001236653],"category_scores_gemma":[0.0001188015,0.000107223,0.0002707493,0.0001087908,0.0000883158,0.0001164922,0.0001271845,0.0004048966,0.0004105148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001323859,"about_ca_system_score_gemma":0.0002026769,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005165171,"about_ca_topic_score_gemma":0.0008959203,"domain_scores_codex":[0.9998862,0.00001676572,0.00001820108,0.00001743068,0.00003488602,0.00002644322],"domain_scores_gemma":[0.9999241,0.00002131638,0.00001496747,0.00001356516,0.00001145666,0.00001460535],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001475768,0.00006149896,0.0002731746,0.00004824905,0.000008446651,0.0001081981,0.00001299359,0.0000582631,0.9971576,0.0000545551,0.00008254671,0.001986926],"study_design_scores_gemma":[0.00001384017,0.0003689114,0.004532215,0.000004142878,0.00001280416,0.0001911411,0.00001355227,0.0003552016,0.9930524,0.00002111656,0.001432235,0.000002474033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952949,0.002052968,0.0009530634,0.0000821117,0.00003425919,0.00002771895,0.0003194473,0.00004640643,0.001189091],"genre_scores_gemma":[0.9931117,0.001392306,0.001007752,0.00005921007,0.00001173165,0.00005351215,0.0009486111,0.00001652996,0.003398684],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001236653,"threshold_uncertainty_score":0.00413698,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02565010608943701,"score_gpt":0.3035433928845297,"score_spread":0.2778932867950927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}