{"id":"W2982674222","doi":"10.15252/embr.201948375","title":"Class I HDAC inhibitors enhance YB‐1 acetylation and oxidative stress to block sarcoma metastasis","year":2019,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Provincial Health Services Authority; University of British Columbia","funders":"Canadian Institutes of Health Research; Terry Fox Research Institute; Michael Smith Health Research BC; Government of Canada","keywords":"Metastasis; Library science; Medicine; Cancer; Oncology; Cancer research; Internal medicine; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000873641,0.0004006004,0.0002324506,0.0002294673,0.00008239425,0.0001601228,0.0002014652,0.0001232761,0.002410725],"category_scores_gemma":[0.00005499605,0.0001058718,0.0001848517,0.0001337021,0.0001679185,0.0001395985,0.0001045629,0.000404052,0.0003922225],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003532518,"about_ca_system_score_gemma":0.0002560709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009016203,"about_ca_topic_score_gemma":0.002882754,"domain_scores_codex":[0.9999515,0.000004838652,0.000003609692,0.000009331879,0.00001447478,0.00001636896],"domain_scores_gemma":[0.9999675,0.000003449023,0.0000103963,0.000003309443,0.000004316319,0.00001110277],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003988585,0.0001046525,0.0002032716,0.0000726947,0.00001508479,0.00002624845,0.000005609255,0.0001721086,0.9917672,0.0002814285,0.0002723023,0.006680442],"study_design_scores_gemma":[0.00009972556,0.0008490701,0.002243111,0.0000053444,0.00002803603,0.0001026179,0.00001022108,0.0005033924,0.9898027,0.00005060409,0.006301335,0.00000388044],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9811024,0.006193443,0.003890109,0.0003055831,0.0001202585,0.00009764248,0.0006654373,0.0004158626,0.007209311],"genre_scores_gemma":[0.9868571,0.003608391,0.002126847,0.00008825971,0.00002779833,0.00003713508,0.0004919416,0.00004086117,0.006721676],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002410725,"threshold_uncertainty_score":0.008064747,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007467732761408658,"score_gpt":0.2781957107401475,"score_spread":0.2707279779787389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}