{"id":"W2982865643","doi":"10.1016/s1470-2045(19)30668-0","title":"Ramucirumab plus docetaxel versus placebo plus docetaxel in patients with locally advanced or metastatic urothelial carcinoma after platinum-based therapy (RANGE): overall survival and updated results of a randomised, double-blind, phase 3 trial","year":2019,"lang":"en","type":"article","venue":"The Lancet Oncology","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency","funders":"National Center for Advancing Translational Sciences; National Cancer Institute; Roche; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Docetaxel; Medicine; Ramucirumab; Clinical endpoint; Internal medicine; Metastatic Urothelial Carcinoma; Population; Oncology; Placebo; Progression-free survival; Surgery; Clinical trial; Chemotherapy; Cancer; Urothelial carcinoma; Bladder cancer; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002131508,0.001642227,0.003611676,0.0004708325,0.0003746256,0.001244633,0.001003829,0.001474178,0.004165639],"category_scores_gemma":[0.001875151,0.000682618,0.003049377,0.0004305741,0.001015697,0.001386381,0.0004177307,0.00351949,0.0009184561],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008469521,"about_ca_system_score_gemma":0.000701279,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001211056,"about_ca_topic_score_gemma":0.003032632,"domain_scores_codex":[0.999122,0.0005007223,0.0000489945,0.0001715569,0.00004439461,0.0001124153],"domain_scores_gemma":[0.9991422,0.0003040913,0.0002268488,0.00007667032,0.00004313915,0.0002069816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9764404,0.001893479,0.0004973907,0.0005987034,0.001394872,0.0000280608,0.0000545056,0.0004339359,0.001121349,0.0000625484,0.000538283,0.01693641],"study_design_scores_gemma":[0.9247552,0.06950711,0.00301206,0.00005559195,0.001134634,0.00004827333,0.00002936449,0.0004426333,0.0002857479,0.0001585626,0.0005450921,0.00002576528],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9792252,0.01433697,0.0004702953,0.0006991838,0.0007409576,0.001151103,0.0009055259,0.0002000204,0.002270856],"genre_scores_gemma":[0.9896986,0.003836627,0.0008616389,0.0007890924,0.0004103939,0.0008093255,0.0007870666,0.0000296933,0.002777649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004165639,"threshold_uncertainty_score":0.01393551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0584573287324271,"score_gpt":0.3466840245943807,"score_spread":0.2882266958619536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}