{"id":"W2982950298","doi":"10.4049/jimmunol.1900781","title":"The Transcription Factor RORα Preserves ILC3 Lineage Identity and Function during Chronic Intestinal Infection","year":2019,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute; BC Cancer Agency; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"RAR-related orphan receptor gamma; Innate lymphoid cell; Transcription factor; Orphan receptor; Biology; Immunology; SOX9; Cell biology; Cancer research; Immunity; Immune system; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001931999,0.0002958324,0.0002811999,0.000225771,0.0001369527,0.0003167732,0.0001586156,0.0002224231,0.0006470346],"category_scores_gemma":[0.0001345049,0.0001290197,0.0001718301,0.0001314307,0.0003664886,0.0001309863,0.000163526,0.0006185609,0.0003699996],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002357518,"about_ca_system_score_gemma":0.0001768105,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005578232,"about_ca_topic_score_gemma":0.0006923925,"domain_scores_codex":[0.9997633,0.00004107279,0.0000166496,0.00003474021,0.00004123154,0.0001029103],"domain_scores_gemma":[0.9997599,0.00002587072,0.00007510675,0.00004426606,0.00002346081,0.00007146473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001238535,0.00000735204,0.0001249185,0.000005772691,0.00000103453,0.00001735177,0.000007030314,0.00001287955,0.9993871,0.00001267124,0.000009340935,0.0002905375],"study_design_scores_gemma":[0.00002811871,0.0006206994,0.01523153,0.00001036385,0.00001807149,0.0003034116,0.0000817558,0.0006437046,0.9813206,0.00004484837,0.001691854,0.000005137261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980059,0.0006177161,0.0007520382,0.00004015024,0.000009810971,0.000007413688,0.0001698183,0.00004269987,0.0003544468],"genre_scores_gemma":[0.9981022,0.0001699638,0.0004774392,0.00003840086,0.000006322111,0.0000130693,0.0002633021,0.00001927277,0.0009099652],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006470346,"threshold_uncertainty_score":0.002164543,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01418054977769953,"score_gpt":0.2265588409247032,"score_spread":0.2123782911470037,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}