{"id":"W2982950298","doi":"10.4049/jimmunol.1900781","title":"The Transcription Factor RORα Preserves ILC3 Lineage Identity and Function during Chronic Intestinal Infection","year":2019,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute; BC Cancer Agency; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"RAR-related orphan receptor gamma; Innate lymphoid cell; Transcription factor; Orphan receptor; Biology; Immunology; SOX9; Cell biology; Cancer research; Immunity; Immune system; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006745875,0.0001450272,0.0002302037,0.00009903713,0.0004774166,0.00003098895,0.0002573927,0.0001847788,0.0001302766],"category_scores_gemma":[0.0001532948,0.00008302653,0.00009707577,0.0001118514,0.0002870346,0.0004785484,0.00007482623,0.0007827611,0.0001236288],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008641907,"about_ca_system_score_gemma":0.00008732726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001429055,"about_ca_topic_score_gemma":0.0002615861,"domain_scores_codex":[0.9985945,0.0005536221,0.000417643,0.0001071921,0.00004935376,0.0002776506],"domain_scores_gemma":[0.9989632,0.0002400317,0.0003896607,0.0002224846,0.0001722248,0.00001237824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001062423,0.0000390517,0.004356375,0.00003012469,0.0003009885,0.000001247527,0.0006785145,0.00001907142,0.9910169,0.0002967515,0.00006322467,0.002135375],"study_design_scores_gemma":[0.003095275,0.002806698,0.7284787,0.0001147342,0.000195682,0.002138613,0.0006821079,0.00001328578,0.2357464,0.0005370495,0.02600332,0.000188135],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853984,0.0107558,0.0006099123,0.000155065,0.002748508,0.0001668669,0.00001707954,0.00002286564,0.0001255556],"genre_scores_gemma":[0.9943342,0.004485784,0.000004245405,0.00001872285,0.0001411783,0.000002412074,0.000004881563,0.00001140103,0.0009971828],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7552705,"threshold_uncertainty_score":0.367195,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01418054977769953,"score_gpt":0.2265588409247032,"score_spread":0.2123782911470037,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}