{"id":"W2982975379","doi":"10.1111/mmi.14407","title":"The UDP‐GalNAcA biosynthesis genes <i>gna</i>‐<i>gne2</i> are required to maintain cell envelope integrity and <i>in vivo</i> fitness in multi‐drug resistant <i>Acinetobacter baumannii</i>","year":2019,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Medical School, University of Michigan; National Institutes of Health; Emory University","keywords":"Biology; Acinetobacter baumannii; Mutant; Cell envelope; Microbiology; Biosynthesis; In vivo; Gene; Antibiotics; Genetics; Bacteria; Escherichia coli; Pseudomonas aeruginosa","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008368556,0.0005383901,0.0006140109,0.000157114,0.0001200518,0.00008470868,0.0007567342,0.0004774366,0.00003018875],"category_scores_gemma":[0.0001577341,0.0004435052,0.0001470739,0.0003117961,0.0003185368,0.00001327243,0.000568439,0.0004021771,0.00005464082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001101632,"about_ca_system_score_gemma":0.0001275241,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001717087,"about_ca_topic_score_gemma":0.002534685,"domain_scores_codex":[0.9963658,0.0006140802,0.0007410709,0.00123094,0.0001020463,0.0009459911],"domain_scores_gemma":[0.9983373,0.0001164861,0.0002466201,0.001043047,0.0001101842,0.0001463399],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007336458,0.000104225,0.04389978,0.00006833494,0.00003736015,0.00006853239,0.00006459824,0.00002642136,0.9533384,0.00004198743,0.001455581,0.00016108],"study_design_scores_gemma":[0.001337457,0.0001413608,0.01143387,0.0001486494,0.00001886396,0.00003750325,0.0003804777,0.00001032477,0.8820341,0.00002927993,0.1038118,0.0006162876],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927094,0.00382038,0.0002793222,0.001409939,0.000320109,0.0009516185,0.0001753455,0.00002094629,0.0003129442],"genre_scores_gemma":[0.9935501,0.0007158241,0.002169501,0.002082911,0.00004654376,0.00004522799,0.00009597174,0.00008192355,0.001211994],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1023562,"threshold_uncertainty_score":0.9998017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006845338172703836,"score_gpt":0.2205819157498218,"score_spread":0.213736577577118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}