{"id":"W2982975379","doi":"10.1111/mmi.14407","title":"The UDP‐GalNAcA biosynthesis genes <i>gna</i>‐<i>gne2</i> are required to maintain cell envelope integrity and <i>in vivo</i> fitness in multi‐drug resistant <i>Acinetobacter baumannii</i>","year":2019,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Medical School, University of Michigan; National Institutes of Health; Emory University","keywords":"Biology; Acinetobacter baumannii; Mutant; Cell envelope; Microbiology; Biosynthesis; In vivo; Gene; Antibiotics; Genetics; Bacteria; Escherichia coli; Pseudomonas aeruginosa","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007605213,0.0004824853,0.0002321078,0.0001727312,0.0001428899,0.0003553048,0.0001688141,0.0002682454,0.0006533671],"category_scores_gemma":[0.0001852893,0.0001286878,0.0002428628,0.0001797805,0.0001889132,0.0001823979,0.0003271464,0.0003872032,0.0003399951],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003575472,"about_ca_system_score_gemma":0.0002866829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001713921,"about_ca_topic_score_gemma":0.001502072,"domain_scores_codex":[0.9998426,0.00002711602,0.00001688628,0.00002746744,0.000055584,0.00003025187],"domain_scores_gemma":[0.9998714,0.00001503078,0.00004344011,0.00001771268,0.00002032912,0.0000321157],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000590833,0.0000139594,0.0006161606,0.0000142735,0.000003701126,0.00006092765,0.000007217306,0.00008419875,0.9983997,0.00004436806,0.00002253141,0.0006739277],"study_design_scores_gemma":[0.000009475769,0.0001704813,0.02772766,0.000005851814,0.00001323324,0.0009700462,0.00006899277,0.002026611,0.9668291,0.00008572412,0.002080431,0.00001231344],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960784,0.0003639764,0.002194928,0.00008668598,0.00001596288,0.00001250003,0.0004391997,0.0000945567,0.0007137276],"genre_scores_gemma":[0.9953453,0.0001665912,0.002340765,0.00005789591,0.000004244204,0.00001613811,0.0009433539,0.00003013766,0.001095594],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001713921,"threshold_uncertainty_score":0.003407896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006845338172703836,"score_gpt":0.2205819157498218,"score_spread":0.213736577577118,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}