{"id":"W2982980901","doi":"10.1093/cvr/cvz311","title":"Nitric oxide modulates cardiomyocyte pH control through a biphasic effect on sodium/hydrogen exchanger-1","year":2019,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"British Heart Foundation","keywords":"Nitric oxide; Sodium–hydrogen antiporter; Intracellular pH; Chemistry; Biophysics; Myocyte; Phosphodiesterase 3; Cell biology; Nitric oxide synthase; Stimulation; Sodium-calcium exchanger; Biochemistry; Intracellular; Sodium; Phosphodiesterase; Enzyme; Endocrinology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002296582,0.0001848848,0.00023083,0.0000659795,0.0000902803,0.0001890273,0.0001783646,0.0002161845,0.0009243063],"category_scores_gemma":[0.000158642,0.00008260548,0.000161118,0.00004388619,0.0002407611,0.0002561735,0.0001948889,0.0003321527,0.0001081993],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001502914,"about_ca_system_score_gemma":0.0001124253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001052016,"about_ca_topic_score_gemma":0.0002406745,"domain_scores_codex":[0.999866,0.00003047043,0.00001245958,0.00003589442,0.00002708089,0.00002804512],"domain_scores_gemma":[0.9999063,0.00002188072,0.00002359181,0.000008660199,0.00001107876,0.00002850795],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003288997,0.00001527043,0.0001730707,0.00005226425,0.000003266363,0.00003079547,0.00001132225,0.00002196586,0.9981228,0.00007473952,0.00002781184,0.001137973],"study_design_scores_gemma":[0.0001257736,0.0009406946,0.02888594,0.00003460918,0.00004340975,0.0002231073,0.00007201301,0.001350066,0.9653829,0.0002200446,0.002711213,0.0000102569],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884436,0.006639896,0.002161313,0.0003303192,0.0001168256,0.00002853871,0.0001966776,0.00003606362,0.002046812],"genre_scores_gemma":[0.9955017,0.001580769,0.001252779,0.0001730527,0.00003575909,0.00002964821,0.00008451516,0.000008232398,0.001333485],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009243063,"threshold_uncertainty_score":0.00309217,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02569328579013208,"score_gpt":0.3085987151902799,"score_spread":0.2829054294001478,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}