{"id":"W2982990174","doi":"10.1080/23723556.2019.1654814","title":"RAS-driven oncogenesis is supported by downstream antioxidant programs","year":2019,"lang":"en","type":"article","venue":"Molecular & Cellular Oncology","topic":"Amino Acid Enzymes and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Carcinogenesis; Antioxidant; Glutathione; Oxidative stress; Cell biology; Gene; Biology; Cystine; Biochemistry; Chemistry; Genetics; Enzyme; Cysteine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001271454,0.0003943667,0.0002129692,0.0003264793,0.0002028475,0.0003663387,0.0001350946,0.0002003622,0.001546121],"category_scores_gemma":[0.0001255148,0.00008817015,0.0002579956,0.0001678296,0.0002762163,0.0001949564,0.0003087399,0.0004437755,0.0003930719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000233149,"about_ca_system_score_gemma":0.0001935849,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003019273,"about_ca_topic_score_gemma":0.000582123,"domain_scores_codex":[0.9998468,0.00002562622,0.000013402,0.00003622945,0.0000519871,0.00002603129],"domain_scores_gemma":[0.9998139,0.00002788594,0.0000534903,0.00002884119,0.00004578467,0.00003020392],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001019503,0.00001751841,0.0004240223,0.00005284725,0.000007805831,0.0001869592,0.00002117642,0.00003667876,0.9964659,0.0004958528,0.00005202882,0.002137209],"study_design_scores_gemma":[0.000007421685,0.0002569792,0.008460329,0.000008615333,0.00003317874,0.0007316999,0.00006067685,0.000565532,0.9819173,0.0003054353,0.007645035,0.000007877096],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800171,0.005279547,0.008101248,0.0005169071,0.0001044855,0.00003775849,0.000559817,0.0004761814,0.004907019],"genre_scores_gemma":[0.9934881,0.001879106,0.001614765,0.00006348095,0.00001635312,0.00001479121,0.0004060579,0.0000224365,0.002494869],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001546121,"threshold_uncertainty_score":0.005172253,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005546429585914649,"score_gpt":0.2338116638153276,"score_spread":0.2282652342294129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}