{"id":"W2982990174","doi":"10.1080/23723556.2019.1654814","title":"RAS-driven oncogenesis is supported by downstream antioxidant programs","year":2019,"lang":"en","type":"article","venue":"Molecular & Cellular Oncology","topic":"Amino Acid Enzymes and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Carcinogenesis; Antioxidant; Glutathione; Oxidative stress; Cell biology; Gene; Biology; Cystine; Biochemistry; Chemistry; Genetics; Enzyme; Cysteine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002337819,0.0004418089,0.000558701,0.00008635296,0.00008236884,0.0000381381,0.0005010091,0.000635744,0.0003245768],"category_scores_gemma":[0.00002194351,0.0004338427,0.0003755378,0.000217828,0.0001684919,0.000008161378,0.0002774867,0.0002164505,0.0003759171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005472293,"about_ca_system_score_gemma":0.0002588206,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007714376,"about_ca_topic_score_gemma":0.00001365663,"domain_scores_codex":[0.9972606,0.0002025738,0.0004727107,0.0009690798,0.0003101259,0.000784934],"domain_scores_gemma":[0.9983771,0.00000955827,0.0002309777,0.0009525834,0.000151252,0.0002784939],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007849681,0.0003618452,0.003019916,0.00002579486,0.0002066884,0.0001048715,0.00005899373,0.00001628096,0.9708714,0.0001119484,0.006703973,0.01843978],"study_design_scores_gemma":[0.0009900244,0.0006301696,0.0002060073,0.000006370079,0.00007263398,0.00004256038,0.00005881262,0.00004773342,0.5663085,0.00001732591,0.4313049,0.0003149032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9835644,0.003868161,0.005810822,0.0003908541,0.0005312123,0.0007667271,0.00005218328,0.00005578228,0.004959827],"genre_scores_gemma":[0.9890566,0.0004834823,0.001814935,0.001902313,0.0001784756,0.00008309963,0.001042572,0.0001012963,0.005337245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.424601,"threshold_uncertainty_score":0.9998114,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005546429585914649,"score_gpt":0.2338116638153276,"score_spread":0.2282652342294129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}