{"id":"W2983081583","doi":"10.1182/blood-2019-126661","title":"Low-Dose Tamoxifen (LDTam) As a Breast Cancer (BC) Risk-Reduction Strategy in Lymphoma Survivors Exposed to Chest Radiation Therapy (RT) during Adolescence/Young Adulthood - a Randomized, Placebo-Controlled Double Blinded Phase IIb Trial","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"Cancer Risks and Factors","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Medicine; Tamoxifen; Breast cancer; Cumulative incidence; Internal medicine; Population; Oncology; Randomized controlled trial; Placebo; Clinical endpoint; Cancer; Pathology; Cohort","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001321315,0.001147886,0.001789107,0.0004062659,0.0003815073,0.0007065783,0.0008374458,0.001983239,0.004773731],"category_scores_gemma":[0.001418325,0.0004218995,0.001667653,0.0003428462,0.0006951993,0.0006569091,0.0003343156,0.001887082,0.0005497005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005150415,"about_ca_system_score_gemma":0.0008297912,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006839103,"about_ca_topic_score_gemma":0.002253745,"domain_scores_codex":[0.999511,0.0002795765,0.00004332038,0.0000819326,0.00003166676,0.00005244892],"domain_scores_gemma":[0.9993333,0.0001954919,0.0001832847,0.00004594353,0.00005648208,0.0001853802],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9536493,0.009248392,0.0009401001,0.00196735,0.001604229,0.00005096324,0.00007104512,0.0003227594,0.004453607,0.0001273082,0.0008424239,0.02672253],"study_design_scores_gemma":[0.9259104,0.07049961,0.001422122,0.00007715506,0.0007145623,0.00003136781,0.00001963395,0.0002382464,0.0003312501,0.0001015135,0.000644746,0.00000948927],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9697841,0.01587146,0.0009936043,0.000916142,0.0005792974,0.008459703,0.001126847,0.0001648581,0.002103884],"genre_scores_gemma":[0.9752019,0.006697598,0.002682154,0.001853956,0.0004749856,0.009835681,0.000790185,0.00002026007,0.002443218],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004773731,"threshold_uncertainty_score":0.01596975,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0150369800890378,"score_gpt":0.2894551881757657,"score_spread":0.2744182080867278,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}