{"id":"W2983167487","doi":"10.1182/blood-2019-128830","title":"A Reproducible and Simple Method to Generate Red Blood Cells from Human Pluripotent Stem Cells","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; Stemcell Technologies","funders":"","keywords":"Induced pluripotent stem cell; Haematopoiesis; Stem cell; Cell biology; Biology; Embryonic stem cell; Progenitor cell; Matrigel; Cell culture; Cellular differentiation; Embryoid body; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001644898,0.0009448914,0.0006275767,0.001529205,0.000812437,0.0007264415,0.0009920945,0.0007445403,0.003993606],"category_scores_gemma":[0.0009365808,0.0006355963,0.0009604261,0.0009208162,0.0004989362,0.0005138674,0.0009833289,0.00184475,0.004967838],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003357682,"about_ca_system_score_gemma":0.001028582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004793539,"about_ca_topic_score_gemma":0.001422842,"domain_scores_codex":[0.9976654,0.000281199,0.0003993408,0.0004476926,0.001096176,0.0001101805],"domain_scores_gemma":[0.999459,0.00008864667,0.00008550374,0.0001663633,0.0001544101,0.00004612312],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003454789,0.0001014255,0.0002281749,0.0003772858,0.00002121499,0.0001934159,0.00008668889,0.0003173086,0.9707327,0.0008421288,0.00225726,0.0248079],"study_design_scores_gemma":[0.00005100852,0.0003519007,0.001583159,0.00009155206,0.00007183133,0.001179091,0.00003281563,0.001424144,0.894347,0.0003567417,0.1004477,0.00006303332],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.06609775,0.008251982,0.8831355,0.000720749,0.0009827514,0.008324794,0.008199587,0.006289274,0.01799771],"genre_scores_gemma":[0.1827976,0.007509067,0.7589262,0.000574325,0.0001913954,0.01116076,0.01654106,0.001055653,0.02124395],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.003993606,"threshold_uncertainty_score":0.0133599,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02362756785768709,"score_gpt":0.2697659779272978,"score_spread":0.2461384100696107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}