{"id":"W2983167487","doi":"10.1182/blood-2019-128830","title":"A Reproducible and Simple Method to Generate Red Blood Cells from Human Pluripotent Stem Cells","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; Stemcell Technologies","funders":"","keywords":"Induced pluripotent stem cell; Haematopoiesis; Stem cell; Cell biology; Biology; Embryonic stem cell; Progenitor cell; Matrigel; Cell culture; Cellular differentiation; Embryoid body; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003125587,0.0002080464,0.0004818947,0.0001015215,0.0000818058,0.00002227148,0.0000833237,0.0001376244,0.0005985028],"category_scores_gemma":[0.00001083163,0.0001817945,0.00008930243,0.0001672076,0.0000202425,0.00003743296,0.0001050934,0.0001891109,0.0003791609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001232024,"about_ca_system_score_gemma":0.00004341035,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001945501,"about_ca_topic_score_gemma":0.00001395975,"domain_scores_codex":[0.9981855,0.0001449944,0.0003248948,0.0008722626,0.0001708377,0.0003015572],"domain_scores_gemma":[0.9986439,0.00006429724,0.00009736083,0.0008638568,0.0000844482,0.0002460766],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001103586,0.0004020139,0.001529655,0.00006048282,0.0001653387,0.00004856429,0.0003324278,0.00003464571,0.9940819,0.00002296587,0.002566698,0.000645016],"study_design_scores_gemma":[0.00461608,0.001118499,0.003953489,0.00004132506,0.0004211361,0.00003643667,0.0001197699,0.00004636505,0.9652323,0.0001093694,0.02408776,0.0002174505],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968151,0.000309507,0.0001881786,0.0003739235,0.0003601274,0.0006502402,0.00003846058,0.0001012937,0.001163131],"genre_scores_gemma":[0.9506543,0.00008818165,0.02798828,0.003248536,0.0009832307,0.00004560726,0.00008703673,0.00007557817,0.01682926],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04616085,"threshold_uncertainty_score":0.7413365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02362756785768709,"score_gpt":0.2697659779272978,"score_spread":0.2461384100696107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}