{"id":"W2983300368","doi":"10.1182/blood-2019-129136","title":"Mutations Affecting RNA Binding Proteins Are a Novel Feature of Mantle Cell Lymphoma","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; McGill University; Spinal Cord Injury BC; Simon Fraser University","funders":"","keywords":"Biology; Exome; Mantle cell lymphoma; Exome sequencing; Genetics; Intron; Exon; Gene; RNA splicing; Lymphoma; Mutation; Cancer research; RNA; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001382417,0.0002546908,0.0001746217,0.0006226962,0.0001934956,0.0003780509,0.0002823655,0.0003596944,0.001078641],"category_scores_gemma":[0.0004475163,0.0001487358,0.0001786428,0.0003937283,0.0003239939,0.0001605501,0.0002581504,0.0002812184,0.0002226247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001960779,"about_ca_system_score_gemma":0.00008040051,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003240785,"about_ca_topic_score_gemma":0.0006036522,"domain_scores_codex":[0.9998035,0.00001156448,0.00001461925,0.00008416442,0.00006107911,0.00002506983],"domain_scores_gemma":[0.9997893,0.00005385563,0.00009228037,0.00002604864,0.00001436638,0.00002420087],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004339605,0.00003575506,0.1741922,0.0001410689,0.00007117513,0.009284884,0.0001641998,0.0007200949,0.7894256,0.0003801586,0.00041956,0.02473141],"study_design_scores_gemma":[0.00005658155,0.0002695645,0.7405438,0.00003932075,0.0001625708,0.08572321,0.0002300647,0.005194254,0.1576923,0.0009630296,0.009097235,0.00002818275],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966635,0.0005064931,0.001650838,0.00006076477,0.000004395309,0.000008883188,0.000409051,0.0001067908,0.0005892923],"genre_scores_gemma":[0.9981003,0.0001475877,0.001208499,0.00004528828,0.000007760038,0.000005043917,0.0002934329,0.00001102793,0.0001810989],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001078641,"threshold_uncertainty_score":0.003608406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007772732491068904,"score_gpt":0.2369462443048231,"score_spread":0.2291735118137542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}