{"id":"W2983433106","doi":"10.3390/antiox8110545","title":"Evidence for an Allosteric S-Nitrosoglutathione Binding Site in S-Nitrosoglutathione Reductase (GSNOR)","year":2019,"lang":"en","type":"article","venue":"Antioxidants","topic":"Redox biology and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University; Apotex (Canada); University of Windsor","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Allosteric regulation; S-Nitrosoglutathione; Chemistry; Reductase; Binding site; Biochemistry; Enzyme; Glutathione","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001017486,0.0001751975,0.0001545755,0.0000578833,0.0001050694,0.0001411762,0.0003206062,0.0002898791,0.001175459],"category_scores_gemma":[0.0001352625,0.0001041041,0.0002270332,0.00005676775,0.0002179075,0.0001247804,0.0001570381,0.000359884,0.00026573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001720124,"about_ca_system_score_gemma":0.0001735375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009073314,"about_ca_topic_score_gemma":0.001046372,"domain_scores_codex":[0.9999458,0.000007163651,0.000003278185,0.00001442772,0.0000187757,0.00001047857],"domain_scores_gemma":[0.9999493,0.0000107842,0.00001514606,0.000004845,0.000006638681,0.00001317455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00020554,0.00007425905,0.002282338,0.0001164911,0.00001498123,0.0001722964,0.00003203029,0.0007303892,0.9930443,0.0009222711,0.0001206449,0.002284434],"study_design_scores_gemma":[0.00008737775,0.0007487448,0.02319756,0.00002936593,0.00006315456,0.0009657333,0.000144694,0.02488689,0.9424697,0.0009944641,0.006384446,0.00002793821],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914982,0.0009878487,0.005464223,0.0002248981,0.00002941612,0.00001458818,0.00007880103,0.0001095118,0.00159258],"genre_scores_gemma":[0.9974222,0.0003468661,0.001665444,0.00004844086,0.000003353188,0.000004115408,0.000100752,0.000005174234,0.0004036736],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001175459,"threshold_uncertainty_score":0.003932297,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05257023783349605,"score_gpt":0.3383213158624876,"score_spread":0.2857510780289915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}