{"id":"W2983661566","doi":"10.4049/jimmunol.1901072","title":"CXCR3 Identifies Human Naive CD8+ T Cells with Enhanced Effector Differentiation Potential","year":2019,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"H2020 European Research Council; National Institute of Allergy and Infectious Diseases; Humanitas Research Hospital; National Science Foundation; Associazione Italiana per la Ricerca sul Cancro; Fondazione Italiana per la Ricerca sul Cancro; Ministero della Salute; Wellcome Trust; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Helmut Horten Stiftung; Institute for Research in Biomedicine; University of Minnesota; Emory University; Giovanni Armenise-Harvard Foundation; Ministry of Science and Higher Education of the Russian Federation","keywords":"CXCR3; Effector; Cytotoxic T cell; Cell biology; Biology; Immunology; Inflammation; Genetics; Chemokine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001542394,0.0001219255,0.0001229011,0.0002590194,0.00009814122,0.0002512127,0.00006939798,0.0002474555,0.002622475],"category_scores_gemma":[0.0001213,0.00008022942,0.00009693619,0.000124956,0.00008552516,0.00008854231,0.0001089316,0.0001516771,0.0007377801],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001049609,"about_ca_system_score_gemma":0.00008043157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003834722,"about_ca_topic_score_gemma":0.0004592866,"domain_scores_codex":[0.9999081,0.00001666017,0.000007694022,0.00002319752,0.00001421438,0.0000300562],"domain_scores_gemma":[0.9999591,0.000009699622,0.000008581857,0.000006188541,0.000006956995,0.000009520101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005321705,0.00004616759,0.006668109,0.00004885784,0.000006304013,0.0001860737,0.00005442954,0.00006295298,0.9848102,0.0001288637,0.0001415878,0.007314244],"study_design_scores_gemma":[0.0002967566,0.002529116,0.2206824,0.00007243527,0.0001084693,0.01191934,0.0003095398,0.005234063,0.7421566,0.0004129654,0.01624989,0.00002847065],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950626,0.001397903,0.001365234,0.00003099214,0.000006650361,0.00004027054,0.0003128012,0.00003833623,0.00174509],"genre_scores_gemma":[0.9965112,0.0002731827,0.001609711,0.00003260811,0.00001033388,0.00002018916,0.0005924191,0.000006556701,0.0009439524],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002622475,"threshold_uncertainty_score":0.008773088,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004471738787079566,"score_gpt":0.2147167875930612,"score_spread":0.2102450488059817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}