{"id":"W2983661566","doi":"10.4049/jimmunol.1901072","title":"CXCR3 Identifies Human Naive CD8+ T Cells with Enhanced Effector Differentiation Potential","year":2019,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"H2020 European Research Council; National Institute of Allergy and Infectious Diseases; Humanitas Research Hospital; National Science Foundation; Associazione Italiana per la Ricerca sul Cancro; Fondazione Italiana per la Ricerca sul Cancro; Ministero della Salute; Wellcome Trust; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Helmut Horten Stiftung; Institute for Research in Biomedicine; University of Minnesota; Emory University; Giovanni Armenise-Harvard Foundation; Ministry of Science and Higher Education of the Russian Federation","keywords":"CXCR3; Effector; Cytotoxic T cell; Cell biology; Biology; Immunology; Inflammation; Genetics; Chemokine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0006433203,0.0002564154,0.0005377454,0.0002284868,0.000321037,0.00003006992,0.0006548405,0.0002486398,0.001585585],"category_scores_gemma":[0.00003132442,0.000149243,0.0001944748,0.0001420706,0.0004218769,0.00023231,0.00009020449,0.0007289045,0.000793917],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000578311,"about_ca_system_score_gemma":0.00008224479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005092243,"about_ca_topic_score_gemma":0.000005807168,"domain_scores_codex":[0.9976029,0.001168503,0.0005938021,0.0001501508,0.00008543152,0.0003992192],"domain_scores_gemma":[0.9981021,0.000378259,0.0008171101,0.0004467338,0.0002443233,0.00001151626],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005313063,0.0001362382,0.0001179469,0.00001374327,0.001338694,0.000005210186,0.001279188,0.0000581404,0.9903926,0.00008215153,0.00032852,0.0009345367],"study_design_scores_gemma":[0.004041663,0.002547873,0.02187373,0.0001005809,0.0001941339,0.0006310404,0.0009019156,0.000001208291,0.9679331,0.00009830025,0.001481647,0.0001948639],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875993,0.008147604,0.001000976,0.0001702543,0.002574533,0.0002987506,0.000005333857,0.00002480242,0.0001784502],"genre_scores_gemma":[0.9937783,0.0006373632,0.0000138441,0.00008070844,0.00005258083,0.000004286907,0.00001522205,0.0000292044,0.005388529],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02245952,"threshold_uncertainty_score":0.9999841,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004471738787079566,"score_gpt":0.2147167875930612,"score_spread":0.2102450488059817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}