{"id":"W2984023454","doi":"10.1182/blood-2019-131018","title":"Sirpαfc Treatment Targets Human Acute Myeloid Leukemia Stem Cells","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Trillium Therapeutics (Canada); Hospital for Sick Children; Princess Margaret Cancer Centre","funders":"","keywords":"CD47; Leukemia; Myeloid leukemia; Immunology; Cancer research; Myeloid; Stem cell; Cancer; Haematopoiesis; Biology; Medicine; Immune system; Internal medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002012126,0.0003600518,0.0006187246,0.0002933329,0.0001825218,0.0003933142,0.000243705,0.0002751497,0.001888978],"category_scores_gemma":[0.0001283868,0.00008888898,0.0003293464,0.0002497942,0.0001649896,0.00009565196,0.0001553484,0.0008087172,0.0006113062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003926923,"about_ca_system_score_gemma":0.000354928,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001779828,"about_ca_topic_score_gemma":0.003123291,"domain_scores_codex":[0.9997649,0.00003004639,0.00001775585,0.00003904255,0.0001062398,0.00004213048],"domain_scores_gemma":[0.9999317,0.00001240658,0.00001002172,0.0000102361,0.00001609383,0.00001951056],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00107794,0.0007167973,0.0009070512,0.0002935826,0.00006078931,0.00014518,0.00008805899,0.001292853,0.974048,0.0001951265,0.001753712,0.01942101],"study_design_scores_gemma":[0.0002262444,0.006720168,0.008039452,0.00002463642,0.00009696784,0.0005571244,0.00006878042,0.002312649,0.9652333,0.00006341766,0.01664741,0.000009831135],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9854221,0.006579935,0.001982577,0.0002042952,0.0001184423,0.0002672908,0.001307007,0.0001786327,0.003939743],"genre_scores_gemma":[0.9866659,0.004360688,0.001844021,0.0002179748,0.00003834611,0.0001699948,0.003004282,0.00002430848,0.003674387],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001888978,"threshold_uncertainty_score":0.006319284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01087056747642187,"score_gpt":0.2235741118755954,"score_spread":0.2127035443991735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}