{"id":"W2984054442","doi":"10.1182/blood-2019-131394","title":"Durable Remission and Long-Term Survival in Relapsed/Refractory (r/r) AML Patients Treated with Guadecitabine, Median Survival Not Reached for Responders after Long Term Follow up from Phase 2 Study of 103 Patients","year":2019,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Internal medicine; Regimen; Medicine; Gastroenterology; Population; Neutropenia; Phases of clinical research; Median follow-up; Surgery; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001448186,0.0003625586,0.0007262899,0.0002251811,0.0003634669,0.0005493747,0.0003069947,0.0005501914,0.00111381],"category_scores_gemma":[0.0008564477,0.0002231269,0.00061771,0.0002215839,0.0003202619,0.0004729351,0.0002840482,0.001080482,0.0003055181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004836312,"about_ca_system_score_gemma":0.0004645187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004079955,"about_ca_topic_score_gemma":0.0006682561,"domain_scores_codex":[0.9996327,0.0001361448,0.00003294245,0.00007349644,0.00005001827,0.00007468261],"domain_scores_gemma":[0.9992241,0.0001594129,0.0002287901,0.00008306276,0.00003739165,0.0002671788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3217655,0.02453431,0.3648195,0.0004800062,0.001616695,0.001483178,0.001456544,0.004471038,0.120474,0.0001900047,0.002616483,0.1560926],"study_design_scores_gemma":[0.04285524,0.3577868,0.5771344,0.00007003293,0.001036627,0.002505624,0.0002686829,0.003199841,0.0112427,0.000184169,0.003656976,0.00005888878],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991527,0.0003187168,0.00009772617,0.0000365666,0.000004564297,0.00005501964,0.000162515,0.00000816161,0.0001641226],"genre_scores_gemma":[0.9984475,0.0001678946,0.0002112957,0.00009556251,0.00002115438,0.0001020001,0.0006937581,0.000004594425,0.0002563033],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001448186,"threshold_uncertainty_score":0.007658839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01991727465509969,"score_gpt":0.2872504440037494,"score_spread":0.2673331693486497,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}