{"id":"W298420276","doi":"10.1139/y08-057","title":"Effect of the putative novel selective ET<sub>A</sub>-receptor antagonist HJP272, a 1,3,6-trisubstituted-2-carboxy-quinol-4-one, on infection-mediated premature deliveryThis article is one of a selection of papers published in the special issue (part 2 of 2) on Forefronts in Endothelin.","year":2008,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Preterm Birth and Chorioamnionitis","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institutes of Health","keywords":"Antagonist; Endothelin receptor; Receptor; Medicine; Phosphoramidon; Endothelin 1; Lipopolysaccharide; Internal medicine; Receptor antagonist; Endocrinology; Blockade; Gestation; Pharmacology; Biology; Pregnancy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004218352,0.0001566643,0.000613539,0.0003758038,0.00007125202,0.000002250488,0.0001256142,0.0002067067,0.0004240046],"category_scores_gemma":[0.0002991583,0.0001081128,0.0001247002,0.0005113041,0.0005054058,0.00009456778,0.000008803866,0.0007174708,9.402313e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001202538,"about_ca_system_score_gemma":0.0007267317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001293904,"about_ca_topic_score_gemma":0.002971878,"domain_scores_codex":[0.9983097,0.0005936965,0.0005273219,0.0001639995,0.000157639,0.000247623],"domain_scores_gemma":[0.9984197,0.0005342347,0.000559353,0.00008870943,0.0002711891,0.0001268212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003327084,0.000316492,0.03507601,0.0001558564,0.000294325,0.00001050067,0.003530359,0.0001142624,0.9552586,0.00002182009,0.001478806,0.0004158842],"study_design_scores_gemma":[0.004023022,0.003095275,0.2167455,0.0001521195,0.0001237018,0.00006247134,0.00005901165,0.00004084366,0.7754564,0.00004230391,0.0001369695,0.00006231632],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997836,0.00009865082,0.000001130091,0.00063894,0.0004751298,0.0004944931,0.0001546292,0.000001833278,0.0002992297],"genre_scores_gemma":[0.9985111,0.0003993534,0.000009152981,0.0006591789,0.0003841495,0.00001339126,0.000009947753,0.000009125612,0.000004624256],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1816695,"threshold_uncertainty_score":0.4642553,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008952769273213382,"score_gpt":0.2470484705875043,"score_spread":0.2380957013142909,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}