{"id":"W2984246397","doi":"10.1016/j.ejca.2019.10.002","title":"Phase II study of CC-486 (oral azacitidine) in previously treated patients with locally advanced or metastatic nasopharyngeal carcinoma","year":2019,"lang":"en","type":"article","venue":"European Journal of Cancer","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Celgene","keywords":"Medicine; Tolerability; Neutropenia; Internal medicine; Nasopharyngeal carcinoma; Adverse effect; Febrile neutropenia; Phases of clinical research; Population; Performance status; Progressive disease; Oncology; Surgery; Gastroenterology; Toxicity; Cancer; Chemotherapy; Radiation therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001501955,0.001017119,0.00201497,0.0003637097,0.0005189795,0.0007268231,0.0009462224,0.000980315,0.005133105],"category_scores_gemma":[0.0008397375,0.0005295451,0.001006639,0.0004550143,0.00076175,0.0005699918,0.0003162279,0.00288759,0.001124499],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007107208,"about_ca_system_score_gemma":0.001768407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001699861,"about_ca_topic_score_gemma":0.004227842,"domain_scores_codex":[0.9996513,0.0001649391,0.00002078626,0.00006046197,0.00004059805,0.00006194414],"domain_scores_gemma":[0.9992149,0.0001368596,0.0001399457,0.00007642694,0.00006934254,0.0003625464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.52411,0.1340874,0.03299165,0.002607015,0.003264787,0.001136073,0.001045828,0.004598859,0.09962544,0.0004072912,0.008322218,0.1878036],"study_design_scores_gemma":[0.4746802,0.4761876,0.0346618,0.00008187705,0.0007384278,0.0008305938,0.0001212459,0.001536742,0.005618782,0.0001802698,0.005326757,0.00003561327],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874829,0.003865066,0.0005777081,0.0004337495,0.0001280318,0.004232384,0.00115288,0.0001040057,0.002023166],"genre_scores_gemma":[0.9839939,0.004013375,0.001630342,0.000673618,0.0001776819,0.003677452,0.002827107,0.00003700333,0.002969456],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005133105,"threshold_uncertainty_score":0.01717192,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02586148359563751,"score_gpt":0.3135574410990551,"score_spread":0.2876959575034176,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}