{"id":"W2984278771","doi":"10.1038/s41598-019-51781-x","title":"Gamma-aminobutyric acid-producing lactobacilli positively affect metabolism and depressive-like behaviour in a mouse model of metabolic syndrome","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":170,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Institute for Nanotechnology; University of Alberta","funders":"University College Cork; Teagasc; Science Foundation Ireland; University of Alberta; Ireland Canada University Foundation","keywords":"Endocrinology; Lactobacillus brevis; Metabolic syndrome; Metabolite; Internal medicine; Biology; Gut flora; Metabolism; Insulin; Glucose uptake; Carbohydrate metabolism; Medicine; Diabetes mellitus; Biochemistry; Lactic acid; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003110369,0.001111355,0.0006486186,0.0009916254,0.0003279727,0.0005385346,0.0003314274,0.000788347,0.001436163],"category_scores_gemma":[0.0001947392,0.0004451202,0.0006122905,0.0003574333,0.0004875484,0.0003668963,0.0004241776,0.002011155,0.0003586272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004013243,"about_ca_system_score_gemma":0.0004567435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001352509,"about_ca_topic_score_gemma":0.00296192,"domain_scores_codex":[0.9996186,0.00008849611,0.00004468387,0.00006837126,0.0000809894,0.00009875542],"domain_scores_gemma":[0.9995913,0.00001587213,0.0001122118,0.00003156507,0.00003622748,0.0002127722],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003868736,0.001507974,0.001353061,0.00008731911,0.00004592862,0.0001393804,0.00007119237,0.0001469786,0.9892533,0.0001216206,0.0002048141,0.003199724],"study_design_scores_gemma":[0.001946867,0.03629896,0.09112464,0.0002287892,0.0004856243,0.001310905,0.0008717159,0.005319246,0.8555386,0.0008396055,0.005926642,0.0001084227],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955878,0.0007829604,0.001259466,0.0004765288,0.00006697248,0.00006191414,0.0007899437,0.0001243362,0.0008501252],"genre_scores_gemma":[0.9858392,0.001694977,0.004119377,0.0004830657,0.0000314462,0.0003290423,0.001117282,0.00007181364,0.006313833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001436163,"threshold_uncertainty_score":0.004804492,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01108455488786542,"score_gpt":0.2484016141498707,"score_spread":0.2373170592620053,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}