{"id":"W2984284890","doi":"10.1038/s41565-019-0567-y","title":"Smart cancer nanomedicine","year":2019,"lang":"en","type":"article","venue":"Nature Nanotechnology","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":1196,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Heart, Lung, and Blood Institute; National Cancer Institute; National Institutes of Health; Helse Midt-Norge; National Science Council; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; ZonMw; Deutsche Forschungsgemeinschaft; European Commission","keywords":"Nanomedicine; Nanocarriers; Medicine; Cancer; Clinical trial; Drug; Immunotherapy; Cancer immunotherapy; Pharmacology; Nanotechnology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002826448,0.0004902874,0.0003853831,0.0004002263,0.0004343903,0.0008839698,0.0004993572,0.001082891,0.009513666],"category_scores_gemma":[0.000272049,0.0002894999,0.0002684944,0.000202796,0.0004699561,0.001030311,0.000987045,0.001208613,0.005840858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005173879,"about_ca_system_score_gemma":0.0004219969,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002085889,"about_ca_topic_score_gemma":0.0004163877,"domain_scores_codex":[0.9998093,0.0000250639,0.000009573343,0.00004636459,0.00008448111,0.00002517904],"domain_scores_gemma":[0.9999144,0.00001796708,0.00001515058,0.00001304638,0.00002355974,0.00001588619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002602,0.0001568706,0.0005865648,0.001065256,0.00007662211,0.000425582,0.0001896597,0.001697664,0.495647,0.0860059,0.0719529,0.3419358],"study_design_scores_gemma":[0.00005023264,0.0003029535,0.0005076025,0.00006935153,0.00003258877,0.0009253293,0.00005366528,0.005540474,0.3534721,0.01180287,0.6272098,0.00003304022],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"review","genre_scores_codex":[0.1279475,0.1599074,0.2058657,0.02682223,0.01377318,0.0006823332,0.00215255,0.00368827,0.4591609],"genre_scores_gemma":[0.596797,0.04689087,0.07352918,0.009963904,0.001793243,0.0005459636,0.001520267,0.0003629736,0.2685966],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.009513666,"threshold_uncertainty_score":0.03182644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004597160753762433,"score_gpt":0.2416904441472622,"score_spread":0.2370932833934997,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}