{"id":"W2984337219","doi":"10.1128/jvi.01600-19","title":"Intact Viral Particle Counts Measured by Flow Virometry Provide Insight into the Infectivity and Genome Packaging Efficiency of Moloney Murine Leukemia Virus","year":2019,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Biology; Murine leukemia virus; Virology; Infectivity; Retrovirus; Virus; Flow cytometry; Viral envelope; Capsid; Virus-like particle; Genome; RNA; Viral vector; Viral replication; Molecular biology; Genetics; Gene; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009840735,0.000623752,0.0004603553,0.001440441,0.0003069394,0.001066272,0.0004433938,0.0008937416,0.001464052],"category_scores_gemma":[0.0009388868,0.0002289705,0.000278479,0.0005246186,0.0005650885,0.001336279,0.0003817769,0.001067761,0.0006088719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005258983,"about_ca_system_score_gemma":0.0002935502,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004093809,"about_ca_topic_score_gemma":0.0003122863,"domain_scores_codex":[0.9993143,0.0001114235,0.00005421014,0.0001664435,0.0002629785,0.00009061742],"domain_scores_gemma":[0.9994472,0.000227799,0.0001121372,0.00005409597,0.0001149648,0.00004384654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009779156,0.00004802824,0.002092173,0.00008757188,0.00001280713,0.00003356488,0.0001116457,0.0003152192,0.9816712,0.001100983,0.000213042,0.01421593],"study_design_scores_gemma":[0.00000952779,0.0002790987,0.01132842,0.00003319201,0.00003029531,0.000246614,0.00008844048,0.008239307,0.974766,0.001368282,0.003571572,0.00003923351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7730225,0.009984019,0.205448,0.0004985824,0.0003778611,0.0002303632,0.003062153,0.001494794,0.005881758],"genre_scores_gemma":[0.8804923,0.005463738,0.1061385,0.0003322293,0.0001503197,0.0002168124,0.002107803,0.0002161662,0.004882102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001464052,"threshold_uncertainty_score":0.00520432,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007382321675082093,"score_gpt":0.2376368701163915,"score_spread":0.2302545484413094,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}