{"id":"W2984471300","doi":"10.1016/j.jacc.2019.09.022","title":"Sodium Glucose Cotransporter-2 Inhibition and Cardiorenal Protection","year":2019,"lang":"en","type":"review","venue":"Journal of the American College of Cardiology","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":84,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sinai Health System; Lunenfeld-Tanenbaum Research Institute; University of Alberta; LMC Diabetes & Endocrinology (Canada); St. Michael's Hospital; University of Toronto; Toronto General Hospital; Diabetes Canada","funders":"","keywords":"Medicine; Canagliflozin; Glycemic; Diabetes mellitus; Nephropathy; Clinical trial; Empagliflozin; Intensive care medicine; Kidney disease; Diabetic nephropathy; Renal function; Internal medicine; Type 2 diabetes; Pharmacology; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008211209,0.000918006,0.002300551,0.001474708,0.0001896809,0.0009616677,0.000882735,0.001219636,0.004366532],"category_scores_gemma":[0.0009935705,0.0002983908,0.0008359386,0.001308986,0.0003761201,0.0007888408,0.0006375801,0.002111594,0.001335779],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000342634,"about_ca_system_score_gemma":0.0008325391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007170233,"about_ca_topic_score_gemma":0.002283518,"domain_scores_codex":[0.9997974,0.00003646726,0.00004228602,0.0000375839,0.00006290008,0.00002331566],"domain_scores_gemma":[0.9995715,0.0001893396,0.0001175151,0.00001125156,0.00007231213,0.00003808097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007674282,0.0002978525,0.0003971888,0.03115223,0.0007811431,0.0001486097,0.00004004572,0.0003042994,0.00127293,0.001989582,0.04645145,0.9163973],"study_design_scores_gemma":[0.0008492708,0.001100446,0.005221738,0.01364843,0.003226627,0.001069231,0.00009657485,0.0003334932,0.001070488,0.00269246,0.9706165,0.00007472839],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001494723,0.9989588,0.00005085335,0.0002081246,0.0002390304,0.000003504553,0.00002045928,0.000005558141,0.0003642607],"genre_scores_gemma":[0.001359555,0.997178,0.0001246981,0.0005280992,0.0003580108,0.000008294111,0.00004767504,0.000001368692,0.000394317],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004366532,"threshold_uncertainty_score":0.01460755,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02805261418346305,"score_gpt":0.2844506100953442,"score_spread":0.2563979959118812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}